Salvifarinin A, a neo-clerodane diterpenoid with a 6/5/7 tricyclic skeleton from Salvia farinacea

doi:10.1016/j.tetlet.2018.06.015

	Salvifarinin A, a neo-clerodane diterpenoid with a 6/5/7 tricyclic skeleton from Salvia farinacea
	Fan, Min1,2 ; Chen, Xue-Jiao 1,2; Wu, Xing-De 1; Shao, Li-Dong 1; Ji, Xu1 ; Zhao, Qin-Shi1
	2018-08-08
发表期刊	TETRAHEDRON LETTERS
ISSN	0040-4039
卷号	59 期号:32 页码:3065-3068
摘要	Salvifarinin A (1), a rearrangement product of Languidulane-type clerodane diterpenoids with a 6/5/7 tricyclic ring skeleton fused with gamma-lactone ring and furan ring, and two new biogenetically related diterpernoids, salvifarinins B (2) and C (3), were isolated from the aerial parts of Salvia farinacea. The absolute configuration of 1 was elucidated by extensive spectroscopic methods, and confirmed by single crystal X-ray diffraction and bio-inspired semisynthesis. The plausible biogenetic pathway was also proposed. Compound 2 displayed a potent effect on reducing hepatic steatosis. (C) 2018 Published by Elsevier Ltd.
关键词	Neo-clerodane Diterpenoids Salvia Farinacea Lipid-lowering Activity
DOI	10.1016/j.tetlet.2018.06.015
语种	英语
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/61700
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Fan, Min,Chen, Xue-Jiao,Wu, Xing-De,et al. Salvifarinin A, a neo-clerodane diterpenoid with a 6/5/7 tricyclic skeleton from Salvia farinacea[J]. TETRAHEDRON LETTERS,2018,59(32):3065-3068.
APA	Fan, Min,Chen, Xue-Jiao,Wu, Xing-De,Shao, Li-Dong,Ji, Xu,&Zhao, Qin-Shi.(2018).Salvifarinin A, a neo-clerodane diterpenoid with a 6/5/7 tricyclic skeleton from Salvia farinacea.TETRAHEDRON LETTERS,59(32),3065-3068.
MLA	Fan, Min,et al."Salvifarinin A, a neo-clerodane diterpenoid with a 6/5/7 tricyclic skeleton from Salvia farinacea".TETRAHEDRON LETTERS 59.32(2018):3065-3068.