Bioactive triterpenoid glycosides from the twigs and leaves of Camellia reticulata
Chen, Qi-Run1,2,4; Li, Dan1,2,5; Qin, Xu-Jie1,2; Liu, Hui1,2; Ni, Wei1,2; Yan, Huan1,2; He, Li3; Zhao, Qing4; Ma, Xiao6; Liu, Hai-Yang1,2
2018-06-01
发表期刊PHYTOCHEMISTRY LETTERS
ISSN1874-3900
卷号25页码:6-11
摘要Four previously undescribed oleanane-type triterpenoid glycosides (dianshanchaosides A-D) were isolated from the twigs and leaves of Camellia reticulata, together with seven known analogues. Their structures were established by comprehensive spectroscopic data and chemical methods The triterpenoid glycosides were evaluated their inhibitory effects on the LPS-induced NO production in RAW264.7 macrophages and cytotoxicities against five human cancer cell lines (HL-60, A-549, SMMC-7721, MCF-7, and SW480). Glycosides 2-6, 9, and 10 displayed significant cytotoxicities against the five human cancer lines with IC50 values in the range of 0.54-9.49 mu M.
关键词Camellia Reticulata Oleanane-type Glycosides Dianshanchaosides A-d Nitric Oxide Inhibition Cytotoxicity
DOI10.1016/j.phytol.2018.03.002
语种英语
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被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/61364
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China
3.Kunming Med Univ, Dept Dermatol, Affiliated Hosp 1, Kunming 650032, Yunnan, Peoples R China
4.Yunnan Univ Tradit Chinese Med, Kunming 650500, Yunnan, Peoples R China
5.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
6.Kunming Botanee Biotech Co Ltd, Kunming 650106, Yunnan, Peoples R China
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GB/T 7714
Chen, Qi-Run,Li, Dan,Qin, Xu-Jie,et al. Bioactive triterpenoid glycosides from the twigs and leaves of Camellia reticulata[J]. PHYTOCHEMISTRY LETTERS,2018,25:6-11.
APA Chen, Qi-Run.,Li, Dan.,Qin, Xu-Jie.,Liu, Hui.,Ni, Wei.,...&Liu, Hai-Yang.(2018).Bioactive triterpenoid glycosides from the twigs and leaves of Camellia reticulata.PHYTOCHEMISTRY LETTERS,25,6-11.
MLA Chen, Qi-Run,et al."Bioactive triterpenoid glycosides from the twigs and leaves of Camellia reticulata".PHYTOCHEMISTRY LETTERS 25(2018):6-11.
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