Bioactive triterpenoid glycosides from the twigs and leaves of Camellia reticulata | |
Chen, Qi-Run1,2,4; Li, Dan1,2,5; Qin, Xu-Jie1,2; Liu, Hui1,2; Ni, Wei1,2; Yan, Huan1,2; He, Li3; Zhao, Qing4; Ma, Xiao6; Liu, Hai-Yang1,2 | |
2018-06-01 | |
发表期刊 | PHYTOCHEMISTRY LETTERS |
ISSN | 1874-3900 |
卷号 | 25页码:6-11 |
摘要 | Four previously undescribed oleanane-type triterpenoid glycosides (dianshanchaosides A-D) were isolated from the twigs and leaves of Camellia reticulata, together with seven known analogues. Their structures were established by comprehensive spectroscopic data and chemical methods The triterpenoid glycosides were evaluated their inhibitory effects on the LPS-induced NO production in RAW264.7 macrophages and cytotoxicities against five human cancer cell lines (HL-60, A-549, SMMC-7721, MCF-7, and SW480). Glycosides 2-6, 9, and 10 displayed significant cytotoxicities against the five human cancer lines with IC50 values in the range of 0.54-9.49 mu M. |
关键词 | Camellia Reticulata Oleanane-type Glycosides Dianshanchaosides A-d Nitric Oxide Inhibition Cytotoxicity |
DOI | 10.1016/j.phytol.2018.03.002 |
语种 | 英语 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/61364 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China 3.Kunming Med Univ, Dept Dermatol, Affiliated Hosp 1, Kunming 650032, Yunnan, Peoples R China 4.Yunnan Univ Tradit Chinese Med, Kunming 650500, Yunnan, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 6.Kunming Botanee Biotech Co Ltd, Kunming 650106, Yunnan, Peoples R China |
推荐引用方式 GB/T 7714 | Chen, Qi-Run,Li, Dan,Qin, Xu-Jie,et al. Bioactive triterpenoid glycosides from the twigs and leaves of Camellia reticulata[J]. PHYTOCHEMISTRY LETTERS,2018,25:6-11. |
APA | Chen, Qi-Run.,Li, Dan.,Qin, Xu-Jie.,Liu, Hui.,Ni, Wei.,...&Liu, Hai-Yang.(2018).Bioactive triterpenoid glycosides from the twigs and leaves of Camellia reticulata.PHYTOCHEMISTRY LETTERS,25,6-11. |
MLA | Chen, Qi-Run,et al."Bioactive triterpenoid glycosides from the twigs and leaves of Camellia reticulata".PHYTOCHEMISTRY LETTERS 25(2018):6-11. |
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