Bioactive Nortriterpenoids from Schisandra grandiflora
Xiao, Wei-Lie1; Gong, Yan-Qing2; Wang, Rui-Rui4; Weng, Zhi-Ying1; Luo, Xiao1; Li, Xiao-Nian1; Yang, Guang-Yu1; He, Fei1; Pu, Jian-Xin1; Yang, Liu-Meng4; Zheng, Yong-Tang4; Lu, Yang; Sun, Han-Dong1
2009-09-01
Source PublicationJOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
Volume72Issue:9Pages:1678-1681
AbstractThree new nortriterpenoids, schigrandilactones A-C (1-3), along with eight known compounds, were isolated from an organic solvent extract of Schisandra grandiflora. Compounds I and 2 feature a spirocyclic moiety in their structures, and compound 3 was characterized with a new oxygenated pattern. The relative configurations of 1 and 3 were determined through single-crystal X-ray experiments. In addition, compounds 1 and 2 displayed cytotoxic activity against two human cancer cell lines, and compound 3 showed anti-HIV-1 inhibition in infected C8166 cells.
KeywordCalycinum Skeleton Longeracemosum Cascade
Subject AreaPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np900292e
Indexed BySCI ; IC
Language英语
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000270855600023
Citation statistics
Cited Times:23[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/4812
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
3.Peking Union Med Coll, Beijing 100050, Peoples R China
4.Chinese Acad Sci, Kunming Inst Zool, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Yunnan, Peoples R China
Recommended Citation
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Xiao, Wei-Lie,Gong, Yan-Qing,Wang, Rui-Rui,et al. Bioactive Nortriterpenoids from Schisandra grandiflora[J]. JOURNAL OF NATURAL PRODUCTS,2009,72(9):1678-1681.
APA Xiao, Wei-Lie.,Gong, Yan-Qing.,Wang, Rui-Rui.,Weng, Zhi-Ying.,Luo, Xiao.,...&Sun, Han-Dong.(2009).Bioactive Nortriterpenoids from Schisandra grandiflora.JOURNAL OF NATURAL PRODUCTS,72(9),1678-1681.
MLA Xiao, Wei-Lie,et al."Bioactive Nortriterpenoids from Schisandra grandiflora".JOURNAL OF NATURAL PRODUCTS 72.9(2009):1678-1681.
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