Bioactive Nortriterpenoids from Schisandra grandiflora
Xiao, Wei-Lie1; Gong, Yan-Qing2; Wang, Rui-Rui4; Weng, Zhi-Ying1; Luo, Xiao1; Li, Xiao-Nian1; Yang, Guang-Yu1; He, Fei1; Pu, Jian-Xin1; Yang, Liu-Meng4; Zheng, Yong-Tang4; Lu, Yang; Sun, Han-Dong1
2009-09-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号72期号:9页码:1678-1681
摘要Three new nortriterpenoids, schigrandilactones A-C (1-3), along with eight known compounds, were isolated from an organic solvent extract of Schisandra grandiflora. Compounds I and 2 feature a spirocyclic moiety in their structures, and compound 3 was characterized with a new oxygenated pattern. The relative configurations of 1 and 3 were determined through single-crystal X-ray experiments. In addition, compounds 1 and 2 displayed cytotoxic activity against two human cancer cell lines, and compound 3 showed anti-HIV-1 inhibition in infected C8166 cells.
关键词Calycinum Skeleton Longeracemosum Cascade
资助信息NSFC [30830115, 20802082]; Chinese Academy of Sciences [KSCX1-YW-R-24]; 973 Program [2009CB522303, 2009CB522306, 2009CB940900]; Scientific and Technological Projects of China [2009ZX09501-029]; Yong Academic and Technical Leader Rising Foundation of Yunnan Province [2006PY01-47]; Natural Science Foundation of Yunnan Province [2005XY04, 2006B0042Q]
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np900292e
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000270855600023
引用统计
被引频次:23[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4812
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
3.Peking Union Med Coll, Beijing 100050, Peoples R China
4.Chinese Acad Sci, Kunming Inst Zool, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Yunnan, Peoples R China
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Xiao, Wei-Lie,Gong, Yan-Qing,Wang, Rui-Rui,et al. Bioactive Nortriterpenoids from Schisandra grandiflora[J]. JOURNAL OF NATURAL PRODUCTS,2009,72(9):1678-1681.
APA Xiao, Wei-Lie.,Gong, Yan-Qing.,Wang, Rui-Rui.,Weng, Zhi-Ying.,Luo, Xiao.,...&Sun, Han-Dong.(2009).Bioactive Nortriterpenoids from Schisandra grandiflora.JOURNAL OF NATURAL PRODUCTS,72(9),1678-1681.
MLA Xiao, Wei-Lie,et al."Bioactive Nortriterpenoids from Schisandra grandiflora".JOURNAL OF NATURAL PRODUCTS 72.9(2009):1678-1681.
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