Involvement of Arachidonic Acid Metabolites Pathway and Nicotinic Acetylcholine Receptors (nAChRs) on Nicotine-induced Contractions (or Relaxations) in the Basilar Artery
Li, Yifan1; Luo, Dan2; Chen, Xuejiao2; Li, Jie2; Yan, Liang1; Li, Tong1; Zhao, Yingliang3; Liu, Hui4; Ji, Xu2; Ma, Xiao1
2017
发表期刊INTERNATIONAL JOURNAL OF PHARMACOLOGY
卷号13期号:1页码:1-10
摘要Smoking is one of the most important risk factors for cerebral circulatory disorders and nicotine is considered to be the major pathogenic compound in cigarette smoke. Amelioration of nicotine-induced vasoconstrictions (or vasodilations) may provide a therapeutic target for the treatment of stroke. This study will review the involvement of arachidonic acid metabolites pathway and nicotinic acetylcholine receptors (nAChRs) on nicotine-induced contractions (or relaxations) in the basilar artery. Arachidonic acid metabolites pathway and nAChRs may be new drug targets and their selectivity antagonists (or agonists) may be new therapeutic drugs for the treatment of stroke.
关键词Basilar Artery Nicotine Vasoconstriction Vasorelaxation Arachidinic Acid Nicotinic Acetylcholine Receptors (Nachrs) Endothelium
DOI10.3923/ijp.2017.1.10
收录类别SCI
语种英语
WOS记录号WOS:000391333500001
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/33759
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Yunnan Agr Univ, Yunnan Res Ctr Adv Tea Proc, Minist Educ, Key Lab Pu Erh Tea Sci, 452 FengYuan St, Kunming 650201, Yunnan, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
3.China Tobacco Yunnan Ind Co Ltd, Ctr Technol, Kunming, Yunnan, Peoples R China
4.Dalian Med Univ, Hosp 2, Urol, Dalian 116021, Liaoning, Peoples R China
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Li, Yifan,Luo, Dan,Chen, Xuejiao,et al. Involvement of Arachidonic Acid Metabolites Pathway and Nicotinic Acetylcholine Receptors (nAChRs) on Nicotine-induced Contractions (or Relaxations) in the Basilar Artery[J]. INTERNATIONAL JOURNAL OF PHARMACOLOGY,2017,13(1):1-10.
APA Li, Yifan.,Luo, Dan.,Chen, Xuejiao.,Li, Jie.,Yan, Liang.,...&Ma, Xiao.(2017).Involvement of Arachidonic Acid Metabolites Pathway and Nicotinic Acetylcholine Receptors (nAChRs) on Nicotine-induced Contractions (or Relaxations) in the Basilar Artery.INTERNATIONAL JOURNAL OF PHARMACOLOGY,13(1),1-10.
MLA Li, Yifan,et al."Involvement of Arachidonic Acid Metabolites Pathway and Nicotinic Acetylcholine Receptors (nAChRs) on Nicotine-induced Contractions (or Relaxations) in the Basilar Artery".INTERNATIONAL JOURNAL OF PHARMACOLOGY 13.1(2017):1-10.
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