Lycojapodine A, a Novel Alkaloid from Lycopodium japonicum
He, Juan1,2; Chen, Xuan-Qin1; Li, Ming-Ming1; Zhao, Yu1; Xu, Gang1; Cheng, Xiao1; Peng, Li-Yan1; Xie, Min-Jin3; Zheng, Yong-Tang4,5; Wang, Yi-Ping6; Zhao, Qin-Shi1
2009-03-19
发表期刊ORGANIC LETTERS
ISSN1523-7060
卷号11期号:6页码:1397-1400
摘要Lycojapodine A, a novel C(16)N-type Lycopodium alkaloid with an unprecedented 6/6/6/7 tetracyclic ring system, was isolated from the club moss Lycopodium japonicum. The structure and relative stereochemistry were elucidated on the basis of spectroscopic data and were further confirmed by X-ray analysis. A possible biosynthetic pathway for 1 was proposed. Its inhibitory activity on acetylcholinestrease and anti-HIV-1 activity were also evaluated.
关键词Inhibiting Acetylcholinesterase Nankakurine-a Complanatum Thunb Hamiltonii
资助信息973 program [2009CB522300]; People's Republic of China ; State Key Laboratory of Phytochemistry Kunming Institute of Botany, Chinese Academy of Sciences [P-06-4]
学科领域Chemistry, Organic
DOI10.1021/ol900079t
收录类别SCI ; IC
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Organic
WOS记录号WOS:000264111100052
引用统计
被引频次:41[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/2905
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Yunnan Univ, Dept Chem, Kunming 650091, Peoples R China
4.Chinese Acad Sci, Kunming Inst Zool, Key Lab Anim Models & Human Dis Mechanisms, Kunming 650223, Peoples R China
5.Chinese Acad Sci, Kunming Inst Zool, Lab Mol Immunopharmacol, Kunming 650223, Peoples R China
6.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
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He, Juan,Chen, Xuan-Qin,Li, Ming-Ming,et al. Lycojapodine A, a Novel Alkaloid from Lycopodium japonicum[J]. ORGANIC LETTERS,2009,11(6):1397-1400.
APA He, Juan.,Chen, Xuan-Qin.,Li, Ming-Ming.,Zhao, Yu.,Xu, Gang.,...&Zhao, Qin-Shi.(2009).Lycojapodine A, a Novel Alkaloid from Lycopodium japonicum.ORGANIC LETTERS,11(6),1397-1400.
MLA He, Juan,et al."Lycojapodine A, a Novel Alkaloid from Lycopodium japonicum".ORGANIC LETTERS 11.6(2009):1397-1400.
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