Structural Characterization and Antioxidative Activity of Lancifonins: Unique Nortriterpenoids from Schisandra lancifolia | |
Shi, Yi-Ming1,3; Yang, Jie2; Xu, Li1,3; Li, Xiao-Nian1; Shang, Shan-Zhai1; Cao, Peng2; Xiao, Wei-Lie1; Sun, Han-Dong1 | |
通讯作者 | Cao, P (reprint author), China Acad Tradit Chinese Med, Lab Cellular & Mol Biol, Jiangsu Branch, Nanjing 210028, Jiangsu, Peoples R China. ; pcao79@yahoo.com ; xwl@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn |
2014-03-07 | |
发表期刊 | ORGANIC LETTERS |
ISSN | 1523-7060 |
卷号 | 16期号:5页码:1370-1373 |
摘要 | Six unique nortriterpenoids, lancifonins A-F (1-6), were isolated from Schisandra lancifolia. Their absolute configurations were determined by X-ray diffraction and ECD calculation. The conformational analysis of 1 was performed due to the unanticipated changes of Cotton effects in its ECD spectrum. Compounds 5 and 6 possess a unique 7/7 fused carbocyclic core with an internal ester bridge between C-9 and C-14, and 5 exhibited protective activity against H2O2-induced oxidative damage on Caco-2 cells. |
关键词 | Lancifodilactone g Micrandilactone Cyclization Chinensis |
学科领域 | Chemistry, Organic |
DOI | 10.1021/ol5001186 |
收录类别 | SCI ; IC |
语种 | 英语 |
WOS记录号 | WOS:000332756400025 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/18050 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.China Acad Tradit Chinese Med, Lab Cellular & Mol Biol, Jiangsu Branch, Nanjing 210028, Jiangsu, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Shi, Yi-Ming,Yang, Jie,Xu, Li,et al. Structural Characterization and Antioxidative Activity of Lancifonins: Unique Nortriterpenoids from Schisandra lancifolia[J]. ORGANIC LETTERS,2014,16(5):1370-1373. |
APA | Shi, Yi-Ming.,Yang, Jie.,Xu, Li.,Li, Xiao-Nian.,Shang, Shan-Zhai.,...&Sun, Han-Dong.(2014).Structural Characterization and Antioxidative Activity of Lancifonins: Unique Nortriterpenoids from Schisandra lancifolia.ORGANIC LETTERS,16(5),1370-1373. |
MLA | Shi, Yi-Ming,et al."Structural Characterization and Antioxidative Activity of Lancifonins: Unique Nortriterpenoids from Schisandra lancifolia".ORGANIC LETTERS 16.5(2014):1370-1373. |
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