Structural Characterization and Antioxidative Activity of Lancifonins: Unique Nortriterpenoids from Schisandra lancifolia
Shi, Yi-Ming1,3; Yang, Jie2; Xu, Li1,3; Li, Xiao-Nian1; Shang, Shan-Zhai1; Cao, Peng2; Xiao, Wei-Lie1; Sun, Han-Dong1
Corresponding AuthorCao, P (reprint author), China Acad Tradit Chinese Med, Lab Cellular & Mol Biol, Jiangsu Branch, Nanjing 210028, Jiangsu, Peoples R China. ; pcao79@yahoo.com ; xwl@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn
2014-03-07
Source PublicationORGANIC LETTERS
ISSN1523-7060
Volume16Issue:5Pages:1370-1373
AbstractSix unique nortriterpenoids, lancifonins A-F (1-6), were isolated from Schisandra lancifolia. Their absolute configurations were determined by X-ray diffraction and ECD calculation. The conformational analysis of 1 was performed due to the unanticipated changes of Cotton effects in its ECD spectrum. Compounds 5 and 6 possess a unique 7/7 fused carbocyclic core with an internal ester bridge between C-9 and C-14, and 5 exhibited protective activity against H2O2-induced oxidative damage on Caco-2 cells.
KeywordLancifodilactone g Micrandilactone Cyclization Chinensis
Subject AreaChemistry, Organic
DOI10.1021/ol5001186
Indexed BySCI ; IC
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Organic
WOS IDWOS:000332756400025
Citation statistics
Cited Times:14[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/18050
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.China Acad Tradit Chinese Med, Lab Cellular & Mol Biol, Jiangsu Branch, Nanjing 210028, Jiangsu, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Shi, Yi-Ming,Yang, Jie,Xu, Li,et al. Structural Characterization and Antioxidative Activity of Lancifonins: Unique Nortriterpenoids from Schisandra lancifolia[J]. ORGANIC LETTERS,2014,16(5):1370-1373.
APA Shi, Yi-Ming.,Yang, Jie.,Xu, Li.,Li, Xiao-Nian.,Shang, Shan-Zhai.,...&Sun, Han-Dong.(2014).Structural Characterization and Antioxidative Activity of Lancifonins: Unique Nortriterpenoids from Schisandra lancifolia.ORGANIC LETTERS,16(5),1370-1373.
MLA Shi, Yi-Ming,et al."Structural Characterization and Antioxidative Activity of Lancifonins: Unique Nortriterpenoids from Schisandra lancifolia".ORGANIC LETTERS 16.5(2014):1370-1373.
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