题名: Kadcoccitones A and B, Two New 6/6/5/5-Fused Tetracyclic Triterpenoids from Kadsura coccinea 作者: Liang, Cheng-Qin 1, 3, 4 ; Shi, Yi-Ming 1, 3 ; Luo, Rong-Hua 2, 3 ; Li, Xing-Yao 1, 3 ; Gao, Zhong-Hua 1, 3 ; Li, Xiao-Nian 1 ; Yang, Liu-Meng 2 ; Shang, Shan-Zhai 1, 3 ; null(李艳) 1 Zheng, Yong-Tang 2 ; Zhang, Hong-Bin 4 ; Xiao, Wei-Lie 1 ; null(孙汉董) 1 刊名: ORGANIC LETTERS
关键词: LANCIFODILACTONE-G
; STEREOCONTROLLED SYNTHESIS
; SCHISANDRA-CHINENSIS
; RING
; NORTRITERPENOIDS
; ROOTS
; ROUTE
; CORE
英文摘要: A pair of new triterpenoid epimers, kadcoccitones A (1) and B (2), together with a new biogenetically related compound kadcoccitone C (3), were isolated from Kadsura coccinea. The epimers featured an unprecedented carbon skeleton with a 6/6/5/5-fused tetracyclic ring system unit and a C-9 side chain. Their structures were determined by spectroscopic data, ECD calculation, and single-crystal X-ray diffraction. Compounds 1 and 3 showed anti-HIV-1 activity with an EC50 value of 47.91 and 32.66 mu g/mL, respectively. 出版日期: 2012-12-21
卷号: 14, 期号: 24, 页码: 6362-6365 DOI标识: 10.1021/ol303168y
语种: 英语
ISSN号: 1523-7060
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/15954
Appears in Collections: 植物化学与西部植物资源持续利用国家重点实验室_期刊论文
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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Yunnan, Peoples R China
Recommended Citation:
Liang, Cheng-Qin; Shi, Yi-Ming; Luo, Rong-Hua; Li, Xing-Yao; Gao, Zhong-Hua; Li, Xiao-Nian; Yang, Liu-Meng; Shang, Shan-Zhai; Li, Yan; Zheng, Yong-Tang; Zhang, Hong-Bin; Xiao, Wei-Lie; Sun, Han-Dong.Kadcoccitones A and B, Two New 6/6/5/5-Fused Tetracyclic Triterpenoids from Kadsura coccinea,ORGANIC LETTERS,2012,14(24):6362-6365
