Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum
Cao, Mingming1,2; Zhang, Yu1; He, Hongping1; Li, Shifei1,2; Huang, Shendian1,2; Chen, Duozhi1,2; Tang, Guihua1,2; Li, Shunlin1; Di, Yingtong1; Hao, Xiaojiang1
2012-06-01
Source PublicationJOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
Volume75Issue:6Pages:1076-1082
AbstractTen new yuzurine-type Daphniphyllum alkaloids, daphmacromines A-J (1-10), along with seven known alkaloids were isolated from the leaves and stems of Daphniphyllum macropodum. Their structures were elucidated by extensive spectroscopic techniques, including 2D NMR spectroscopy and mass spectrometry, and the structure of 1 was confirmed by single-crystal X-ray diffraction. The pesticidal and cytotoxic activities of the isolated alkaloids were evaluated in vitro against brine shrimp (Artemia sauna) and five human cancer cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW480), respectively. This study also suggested structural revisions of oxodaphnigracine, oxodaphnigraciline, and epioxodaphnigraciline.
KeywordSkeleton Cascade Humile Assay Miq
DOI10.1021/np200960z
Indexed BySCI ; IC
Language英语
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000305503500011
Citation statistics
Cited Times:24[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/15762
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
Recommended Citation
GB/T 7714
Cao, Mingming,Zhang, Yu,He, Hongping,et al. Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum[J]. JOURNAL OF NATURAL PRODUCTS,2012,75(6):1076-1082.
APA Cao, Mingming.,Zhang, Yu.,He, Hongping.,Li, Shifei.,Huang, Shendian.,...&Hao, Xiaojiang.(2012).Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum.JOURNAL OF NATURAL PRODUCTS,75(6),1076-1082.
MLA Cao, Mingming,et al."Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum".JOURNAL OF NATURAL PRODUCTS 75.6(2012):1076-1082.
Files in This Item: Download All
File Name/Size DocType Version Access License
np200960z.pdf(845KB) 开放获取CC BY-NC-NDView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Cao, Mingming]'s Articles
[Zhang, Yu]'s Articles
[He, Hongping]'s Articles
Baidu academic
Similar articles in Baidu academic
[Cao, Mingming]'s Articles
[Zhang, Yu]'s Articles
[He, Hongping]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Cao, Mingming]'s Articles
[Zhang, Yu]'s Articles
[He, Hongping]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: np200960z.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.