Przewalskone: a cytotoxic adduct of a danshenol type terpenoid and an icetexane diterpenoid via hetero-Diels-Alder reaction from Salvia przewalskii | |
Xu, Gang; Yang, Xing-Wei; Wu, Chun-Yan; Li, Xiao-Nian; Su, Jia; Deng, Xu; Li, Yan; Qin, Hong-Bo; Yang, Li-Xin; Zhao, Qin-Shi | |
通讯作者 | Xu, G (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China, xugang008@mail.kib.ac.cn |
2012 | |
发表期刊 | CHEMICAL COMMUNICATIONS |
ISSN | 1359-7345 |
卷号 | 48期号:37页码:4438-4440 |
摘要 | Przewalskone (1), an unprecedented adduct of two different terpenoid units via a hetero-Diels-Alder cycloaddition, was isolated from the roots of Salvia przewalskii. The structure and absolute configurations were elucidated by extensive analysis of NMR spectra and crystal X-ray diffractions. Compound 1 exhibited significant cytotoxicities against five human cancer lines in vitro (IC50 0.69-2.35 mu M). |
关键词 | Ligularia Species Eremophilanes Oplopanes Phenylpropenoids Dna Introgression Chemotaxonomy Sinapyl Alcohol Derivatives Eremophilane-type Sesquiterpenoids Polyacetylenic Compounds Southwestern Sichuan Medicinal-plants Constituents Diversity Nelumbifolia Senecioneae Veitchiana |
学科领域 | Chemistry, Multidisciplinary |
DOI | 10.1039/c2cc30405h |
收录类别 | SCI ; IC |
语种 | 英语 |
WOS记录号 | WOS:000302559100013 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/10349 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China |
推荐引用方式 GB/T 7714 | Xu, Gang,Yang, Xing-Wei,Wu, Chun-Yan,et al. Przewalskone: a cytotoxic adduct of a danshenol type terpenoid and an icetexane diterpenoid via hetero-Diels-Alder reaction from Salvia przewalskii[J]. CHEMICAL COMMUNICATIONS,2012,48(37):4438-4440. |
APA | Xu, Gang.,Yang, Xing-Wei.,Wu, Chun-Yan.,Li, Xiao-Nian.,Su, Jia.,...&Zhao, Qin-Shi.(2012).Przewalskone: a cytotoxic adduct of a danshenol type terpenoid and an icetexane diterpenoid via hetero-Diels-Alder reaction from Salvia przewalskii.CHEMICAL COMMUNICATIONS,48(37),4438-4440. |
MLA | Xu, Gang,et al."Przewalskone: a cytotoxic adduct of a danshenol type terpenoid and an icetexane diterpenoid via hetero-Diels-Alder reaction from Salvia przewalskii".CHEMICAL COMMUNICATIONS 48.37(2012):4438-4440. |
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