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Synthesis of selective 11 beta-HSD1 inhibitors based on dammarane scaffold 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 135, 页码: 324-338
作者:  Shao, Li-Dong;  Bao, Ying;  Shen, Yu;  Su, Jia;  Leng, Ying;  Zhao, Qin-Shi
Adobe PDF(1336Kb)  |  收藏  |  浏览/下载：301/68  |  提交时间：2017/07/31
11 Beta-hsd1 Inhibitor  Hupehenols  Dammarane  Sar  
The opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 977-989
作者:  Yi, Shou-pu;  Kong, Qing-hong;  Li, Yu-lei;  Pan, Chen-ling;  Yu, Jie;  Cui, Ben-qiang;  Wang, Ying-fei;  Wang, Guan-lin;  Zhou, Pei-lan;  Wang, Li-li;  Gong, Ze-hui;  Su, Rui-bin;  Shen, Yue-hai;  Yu, Gang;  Chang, Kwen-jen
Adobe PDF(854Kb)  |  收藏  |  浏览/下载：333/64  |  提交时间：2017/08/29
Opioid Receptor  Mixed Agonist  Dpi-125  Analgesia  Respiratory Depression  Addiction  
Hupehenols A-E, Selective 11 beta-Hydroxysteroid Dehydrogenase Type 1 (11 beta-HSD1) Inhibitors from Viburnum hupehense 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2015, 卷号: 78, 期号: 2, 页码: 330-334
作者:  Chen, Xuan-Qin;  Shao, Li-Dong;  Pal, Mahesh;  Shen, Yu;  Cheng, Xiao;  Xu, Gang;  Peng, Li-Yan;  Wang, Kou;  Pan, Zheng-Hong;  Li, Ming-Ming;  Leng, Ying;  He, Juan;  Zhao, Qin-Shi;  He,J (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Yunnan,Peoples R China.;  hejuan@mail.kib.ac.cn;  qinshizhao@mail.kib.ac.cn
浏览  |  Adobe PDF(811Kb)  |  收藏  |  浏览/下载：298/86  |  提交时间：2015/06/29
Discovery and structure-activity relationships of ent-Kaurene diterpenoids as potent and selective 11 beta-HSD1 inhibitors: Potential impact in diabetes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 65, 页码: 403-414
作者:  Deng, Xu;  Shen, Yu;  Yang, Jing;  He, Juan;  Zhao, Yu;  Peng, Li-Yan;  Leng, Ying;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1215Kb)  |  收藏  |  浏览/下载：400/150  |  提交时间：2013/10/16
Ent-kaurene Diterpenoids  Structure-activity Relationship Studies  Selective 11 Beta-hsd1 Inhibitors  Urea Derivatives  Diabetes  
Cycloartane and Friedelane Triterpenoids from the Leaves of Caloncoba glauca and Their Evaluation for Inhibition of 11 beta-Hydroxysteroid Dehydrogenases 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2012, 卷号: 75, 期号: 4, 页码: 599-604
作者:  Mpetga, James D. Simo;  Shen, Yu;  Tane, Pierre;  Li, Shi-Fei;  He, Hong-Ping;  Wabo, Hippolyte K.;  Tene, Mathieu;  Leng, Ying;  Hao, Xiao-Jiang
Adobe PDF(347Kb)  |  收藏  |  浏览/下载：397/150  |  提交时间：2012/06/07
Cimicifuga Foetida  4 Alpha-methyl Steroid  Cytotoxicity  Cimisterol a  Performance Liquid-chromatography  Light-scattering Detection  Black Cohosh Products  Euphorbia-chamaesyce  Sequence Variation  Actaea-racemosa  Whole Herb  Triterpenoids  Constituents  Identification  
Pseudoferic acids A-C, three novel triterpenoids from the root bark of Pseudolarix kaempferi 期刊论文
TETRAHEDRON LETTERS, 2012, 卷号: 53, 期号: 7, 页码: 800-803
作者:  Wu, Xing-De;  He, Juan;  Shen, Yu;  Dong, Liao-Bin;  Pan, Zheng-Hong;  Xu, Gang;  Gong, Xun;  Song, Liu-Dong;  Leng, Ying;  Li, Yan;  Peng, Li-Yan;  Zhao, Qin-Shi
Adobe PDF(380Kb)  |  收藏  |  浏览/下载：707/122  |  提交时间：2012/06/07
Pseudolarix Kaempferi  Triterpenoids  11 Beta-hsd1 Inhibitory Activity  
Experimental and computational insights into the conformations of tunicyclin E, a new cycloheptapeptide from Psammosilene tunicoides 期刊论文
RSC ADVANCES, 2012, 卷号: 2, 期号: 3, 页码: 1126-1135
作者:  Tian, Jun-Mian;  Ou-Yang, Si-Sheng;  Zhang, Xu;  Di, Ying-Tong;  Jiang, Hua-Liang;  Li, Hong-Lin;  Dai, Wei-Xing;  Chen, Ke-Yu;  Liu, Mai-Li;  Hao, Xiao-Jiang;  Shen, Yun-Heng;  Luo, Cheng;  Zhang, Wei-Dong
Adobe PDF(820Kb)  |  收藏  |  浏览/下载：725/170  |  提交时间：2012/06/07
Human-induced Erosion  Land Degradation  Logistic Regression  Natural Erosion  Soil Conservation Policy  Highlands  Decision  Ethiopia  Behavior  China  Area  Risk  
Cyclopeptide Alkaloids from Ziziphus apetala 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2011, 卷号: 74, 期号: 12, 页码: 2571-2575
作者:  Han, Jing;  Ji, Chang-Jiu;  He, Wen-Jun;  Shen, Yu;  Leng, Ying;  Xu, Wen-Yan;  Fan, Jun-Ting;  Zeng, Guang-Zhi;  Kong, Ling-Dong;  Tan, Ning-Hua
Adobe PDF(213Kb)  |  收藏  |  浏览/下载：423/162  |  提交时间：2012/04/10
Rare merosesquiterpenoids from basidiomycete Craterellus odoratus and their inhibition of 11 beta-hydroxysteroid dehydrogenases 期刊论文
PHYTOCHEMISTRY, 2010, 卷号: 71, 期号: 1, 页码: 100-103
作者:  Zhang, Ling;  Shen, Yu;  Wang, Fei;  Leng, Ying;  Liu, Ji-Kai
Adobe PDF(179Kb)  |  收藏  |  浏览/下载：338/80  |  提交时间：2011/11/24
Craterellus Odoratus  Basidiomycete  Epoxymethylenecyclohexanetriol-bicyclofarnesane  Merosesquiterpenoids  Craterellins A-c  
Mycorrhizal synthesis of Tuber indicum with two indigenous hosts, Castanea mollissima and Pinus armandii 期刊论文
MYCORRHIZA, 2009, 卷号: 19, 期号: 7, 页码: 461-467
作者:  Geng, Li-Ying;  Wang, Xiang-Hua;  Yu, Fu-Qiang;  Deng, Xiao-Juan;  Tian, Xiao-Fei;  Shi, Xiao-Fei;  Xie, Xue-Dan;  Liu, Pei-Gui;  Shen, Yu-Ying
Adobe PDF(384Kb)  |  收藏  |  浏览/下载：386/155  |  提交时间：2011/12/20
Asian Black Truffle  Ectomycorrhizal Fungi  Its-rdna  Morphology