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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：341/77  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
收藏  |  浏览/下载：225/0  |  提交时间：2018/07/16
Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC  
The Natural Diterpenoid Isoforretin A Inhibits Thioredoxin-1 and Triggers Potent ROS-Mediated Antitumor Effects 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 4, 页码: 926-936
作者:  Sun, Xiaoyan;  Wang, Weiguang;  Chen, Jiao;  Cai, Xueting;  Yang, Jie;  Yang, Yang;  Yan, Huaijiang;  Cheng, Xiaolan;  Ye, Juan;  Lu, Wuguang;  Hu, Chunping;  Sun, Handong;  Pu, Jianxin;  Cao, Peng
浏览  |  Adobe PDF(1370Kb)  |  收藏  |  浏览/下载：503/232  |  提交时间：2017/02/28
7,8-Secolignans from Schisandra wilsoniana and Their Anti-HIV-1 Activities 期刊论文
CHEMISTRY & BIODIVERSITY, 2010, 卷号: 7, 期号: 11, 页码: 2692-2701
作者:  Zhang, Xing-Jie;  Yang, Guang-Yu;  Wang, Rui-Rui;  Pu, Jian-Xin;  Sun, Han-Dong;  Xiao, Wei-Lie;  Zheng, Yong-Tang
Adobe PDF(264Kb)  |  收藏  |  浏览/下载：381/132  |  提交时间：2011/11/24
Schilancidilactones A and B: two novel tetranortriterpenoids with an unprecedented skeleton from Schisandra lancifolia 期刊论文
TETRAHEDRON LETTERS, 2009, 卷号: 50, 期号: 43, 页码: 5962-5964
作者:  Luo, Xiao;  Chang, Ying;  Zhang, Xing-Jie;  Pu, Jian-Xin;  Gao, Xue-Mei;  Wu, Ying-Li;  Wang, Rui-Rui;  Xiao, Wei-Lie;  Zheng, Yong-Tang;  Lu, Yang;  Chen, Guo-Qiang;  Zheng, Qi-Tai;  Sun, Han-Dong
Adobe PDF(302Kb)  |  收藏  |  浏览/下载：393/128  |  提交时间：2012/03/21
Schisandra Lancifolia  Schilancidilactones a And b  Tetranortriterpenoid  Anti-hiv Activity  
Structure Elucidation and Theoretical Investigation of Key Steps in the Biogenetic Pathway of Schisanartane Nortriterpenoids by Using DFT Methods 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2008, 卷号: 14, 期号: 36, 页码: 11584-11592
作者:  Xiao, Wei-Lie;  Lei, Chun;  Ren, Jie;  Liao, Tou-Gen;  Pu, Jian-Xin;  Pittman, Charles U., Jr.;  Lu, Yang;  Zheng, Yong-Tang;  Zhu, Hua-Jie;  Sun, Han-Dong
Adobe PDF(502Kb)  |  收藏  |  浏览/下载：360/139  |  提交时间：2011/11/24
Biogenetic Pathway  Biological Activity  Density Functional Calculations  Nortriterpenoids  X-ray Absorption Spectroscopy