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Dual Carbamoylations on the Polyketide and Glycosyl Moiety by Asm21 Result in Extended Ansamitocin Biosynthesis 期刊论文
CHEMISTRY & BIOLOGY, 2011, 卷号: 18, 期号: 12, 页码: 1571-1580
作者:  Li, Yan;  Zhao, Peiji;  Kang, Qianjin;  Ma, Juan;  Bai, Linquan;  Deng, Zixin
Adobe PDF(986Kb)  |  收藏  |  浏览/下载：356/99  |  提交时间：2012/07/25
Antitumor Agent Ansamitocin  Beta-lactam Antibiotics  Actinosynnema-pretiosum  Gene-cluster  Dna Gyrase  Concanamycin-a  Streptomyces  Novobiocin  Carbamoyltransferase  Inhibitors  
DAPK1 mediates the G1 phase arrest in human nasopharyngeal carcinoma cells induced by grifolin, a potential antitumor natural product 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2011, 卷号: 670, 期号: 2-3, 页码: 427-434
作者:  Luo, Xiang-jian;  Li, Wei;  Yang, Li-fang;  Yu, Xin-fang;  Xiao, Lan-bo;  Tang, Min;  Dong, Xin;  Deng, Qi-pan;  Bode, Ann M.;  Liu, Ji-kai;  Cao, Ya
Adobe PDF(1137Kb)  |  收藏  |  浏览/下载：470/143  |  提交时间：2012/04/10
Grifolin  Dapk1  Cell Cycle  P21  Erk1/2  Npc  Mushroom  
Various mechanisms in cyclopeptide production from precursors synthesized independently of non-ribosomal peptide synthetases 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2011, 卷号: 43, 期号: 10, 页码: 757-762
作者:  Xu, Wenyan;  Li, Liling;  Du, Liangcheng;  Tan, Ninghua
Adobe PDF(163Kb)  |  收藏  |  浏览/下载：280/96  |  提交时间：2012/04/10
Ribosomal Peptide  Cyclopeptides  Non-ribosomal Peptide Synthetase  Cyclization Mechanism  
A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/beta-catenin signaling and colon cancer cell tumorigenesis 期刊论文
CELL RESEARCH, 2011, 卷号: 21, 期号: 5, 页码: 730-740
作者:  Wang, Wei;  Liu, Haiyang;  Wang, Sheng;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(1539Kb)  |  收藏  |  浏览/下载：272/33  |  提交时间：2012/07/25
Wnt  Small Molecule  Inhibitor  Tumorigenesis  
Protein-based alignment in 3D-QSAR of FBPase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 3, 页码: 885-892
作者:  Yi, Ping;  Di, Ying-Tong;  Liu, Wei;  Hao, Xiao-Jiang;  Ming, Yong;  Huang, Du-Shu;  Yang, Jin;  Yi, Zhong-Zhou;  Li, Zi-Jing;  Yang, Rui-Dong;  Zhang, Ju-Cheng
Adobe PDF(777Kb)  |  收藏  |  浏览/下载：394/162  |  提交时间：2012/04/10
3d-qsar  Gold  Comfa  Fbpase  
Gastrodia elata modulates amyloid precursor protein cleavage and cognitive functions in mice 期刊论文
BIOSCIENCE TRENDS, 2011, 卷号: 5, 期号: 3, 页码: 129-138
作者:  Mishra, Manisha;  Huang, Junjie;  Lee, Yin Yeng;  Chua, Doreen See Kin;  Lin, Xiaoyan;  Hu, Jiang-Miao;  Heese, Klaus
浏览  |  Adobe PDF(389Kb)  |  收藏  |  浏览/下载：143/49  |  提交时间：2015/08/17
Alzheimer's Disease  Beta-amyloid Precursor Protein  Kampo  Neurodegeneration  Traditional Chinese Medicine  
Grifolin, a potent antitumour natural product upregulates death-associated protein kinase 1 DAPK1 via p53 in nasopharyngeal carcinoma cells 期刊论文
EUROPEAN JOURNAL OF CANCER, 2011, 卷号: 47, 期号: 2, 页码: 316-325
作者:  Luo, Xiang-jian;  Li, Li-li;  Deng, Qi-pan;  Yu, Xin-fang;  Yang, Li-fang;  Luo, Fei-jun;  Xiao, Lan-bo;  Chen, Xiao-yan;  Ye, Mao;  Liu, Ji-kai;  Cao, Ya
Adobe PDF(1466Kb)  |  收藏  |  浏览/下载：546/164  |  提交时间：2012/04/10
Grifolin  Mushroom  Dapk1  P53  Apoptosis