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The discovery, design and synthesis of potent agonists of adenylyl cyclase type 2 by virtual screening combining biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020
作者:  Xu, Guowei;  Yang, Yaqing;  Yang, Yanming;  Song, Gao;  Li, Shanshan;  Zhang, Jiajun;  Yang, Weimin;  Wang, Liang-Liang;  Weng, Zhiying;  Zuo, Zhili
浏览  |  Adobe PDF(2526Kb)  |  收藏  |  浏览/下载：131/32  |  提交时间：2021/01/05
Synthesis, structure activity relationship and in vitro anti-influenza virus activity of novel polyphenol-pentacyclic triterpene conjugates 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 163, 页码: 560-568
作者:  Li, Haiwei;  Li, Man;  Xu, Renyang;  Wang, Shouxin;  Zhang, Yongmin;  Zhang, Lihe;  Zhou, Demin;  Xiao, Sulong
浏览  |  Adobe PDF(1830Kb)  |  收藏  |  浏览/下载：228/31  |  提交时间：2019/03/25
Influenza virus  Pentacyclic triterpene  Polyphenol  Entry inhibitor  Hemagglutinin  
Synthesis and biological evaluation of magnolol derivatives as melatonergic receptor agonists with potential use in depression 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 期号: 0, 页码: 381-393
作者:  Yang, Tong-Hua;  Ma, Yun-Bao;  Geng, Chang-An;  Yan, De-Xiu;  Huang, Xiao-Yan;  Li, Tian-Ze;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(2088Kb)  |  收藏  |  浏览/下载：239/76  |  提交时间：2018/10/04
Depression  Magnolol Derivatives  Mt1/2 Receptors  Metabolites  Monoamine Neurotransmitter  
Anti-angiogenesis and immunomodulatory activities of an anti-tumor sesquiterpene bigelovin isolated from Inula helianthus-aquatica 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 59, 页码: 243-252
作者:  Yue, Grace G. L.;  Chan, Ben C. L.;  Kwok, Hin-Fai;  Wong, Yuk-Lau;  Leung, Hoi-Wing;  Ji, Chang-Jiu;  Fung, Kwok-Pui;  Leung, Ping-Chung;  Tan, Ning-Hua;  Lau, Clara B. S.
浏览  |  Adobe PDF(1804Kb)  |  收藏  |  浏览/下载：173/47  |  提交时间：2015/05/12
Bigelovin  Inula Helianthus-aquatica  Angiogenesis  Zebrafish  Hmec-1  Cell Adhesion Molecules  
Protein-based alignment in 3D-QSAR of FBPase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 3, 页码: 885-892
作者:  Yi, Ping;  Di, Ying-Tong;  Liu, Wei;  Hao, Xiao-Jiang;  Ming, Yong;  Huang, Du-Shu;  Yang, Jin;  Yi, Zhong-Zhou;  Li, Zi-Jing;  Yang, Rui-Dong;  Zhang, Ju-Cheng
Adobe PDF(777Kb)  |  收藏  |  浏览/下载：410/166  |  提交时间：2012/04/10
3d-qsar  Gold  Comfa  Fbpase  
3D QSAR studies on ketoamides of human cathepsin K inhibitors based on two different alignment methods 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 卷号: 45, 期号: 2, 页码: 667-681
作者:  Pan, Xulin;  Tan, Ninghua;  Zeng, Guangzhi;  Huang, Huoqiang;  Yan, He
Adobe PDF(2690Kb)  |  收藏  |  浏览/下载：377/148  |  提交时间：2012/03/21
Cathepsin k  Comfa  Comsia  Ketoamides  
Synthesis and anticancer activity of lipophilic platinum(II) complexes of 3,5-diisopropylsalicylate 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 卷号: 43, 期号: 7, 页码: 1438-1443
作者:  Yu, Yao;  Lou, Li-Guang;  Liu, Wei-Ping;  Zhu, Hua-Jie;  Ye, Qing-Song;  Chen, Xi-Zhu;  Gao, Wen-Gui;  Hou, Shu-Qian
Adobe PDF(432Kb)  |  收藏  |  浏览/下载：1037/286  |  提交时间：2011/12/19
Lipophilic  Platinum(Ii) Complexes  Antitumor Activity  3  5-diisopropylsalicylic Acid  
3D-QSAR studies of Checkpoint Kinase Weel inhibitors based on molecular docking, CoMFA and CoMSIA 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 卷号: 43, 期号: 5, 页码: 925-938
作者:  Yi, Ping;  Fang, Xin;  Qiu, Minghua
Adobe PDF(2704Kb)  |  收藏  |  浏览/下载：329/99  |  提交时间：2011/11/24
3d-qsar  Gold  Comfa  Comsia  Checkpoint Kinase Weel  
Natural biflavones as novel inhibitors of cathepsin B and K 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2006, 卷号: 41, 期号: 11, 页码: 1247-1252
作者:  Zeng, G. -Z.;  Pan, X. -L.;  Tan, N. -H.;  Xiong, J.;  Zhang, Y. M.
Adobe PDF(604Kb)  |  收藏  |  浏览/下载：343/148  |  提交时间：2011/11/24
Biflavones  Inhibitors  Cathepsin b  Cathepsin k  Docking