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Anticoagulant and antithrombotic evaluation of native fucosylated chondroitin sulfates and their derivatives as selective inhibitors of intrinsic factor Xase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 92, 页码: 257-269
作者:  Wu, Mingyi;  Wen, Dandan;  Gao, Na;  Xiao, Chuang;  Yang, Lian;  Xu, Li;  Lian, Wu;  Peng, Wenlie;  Jiang, Jianmin;  Zhao, Jinhua;  Jiang,JM (reprint author),Sun Yat Sen Univ,Sch Pharmaceut Sci,Guangzhou 510006,Guangdong,Peoples R China.;  lssjjm@mail.sysu.edu.cn;  zhao.jinhua@yahoo.com
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Fucosylated Chondroitin Sulfate  Factor Xase Inhibitor  Anticoagulant  Antithrombotic  Structure-activity Relationship  
Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
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2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
Discovery and structure-activity relationships of ent-Kaurene diterpenoids as potent and selective 11 beta-HSD1 inhibitors: Potential impact in diabetes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 65, 页码: 403-414
作者:  Deng, Xu;  Shen, Yu;  Yang, Jing;  He, Juan;  Zhao, Yu;  Peng, Li-Yan;  Leng, Ying;  Zhao, Qin-Shi
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Ent-kaurene Diterpenoids  Structure-activity Relationship Studies  Selective 11 Beta-hsd1 Inhibitors  Urea Derivatives  Diabetes  
Design, synthesis, and molecular hybrids of caudatin and cinnamic acids as novel anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 54, 页码: 352-365
作者:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Luo, Jie;  Huang, Xiao-Yan;  Chen, Hao;  Zhou, Ning-Jia;  Zhang, Xue-Mei;  Chen, Ji-Jun
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Synthesis  Molecular Hybrids  Caudatin Derivatives  Anti-hepatitis b Virus  Unique Mechanisms  
Structure-activity relationships study of 6-chloro-4-(2-chlorophenyl)-3-(2-hydroxyethyl) quinolin-2(1H)-one derivatives as novel non-nucleoside anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 1, 页码: 307-319
作者:  Guo, Rui-Hua;  Zhang, Quan;  Ma, Yun-Bao;  Luo, Jie;  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Zhou, Jun;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(866Kb)  |  收藏  |  浏览/下载：371/96  |  提交时间：2012/04/10
Anti-hepatitis b Virus Activity  Quinolin-2(1h)-one  Structure-activity Relationships  
Synthesis and anticancer activity of lipophilic platinum(II) complexes of 3,5-diisopropylsalicylate 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 卷号: 43, 期号: 7, 页码: 1438-1443
作者:  Yu, Yao;  Lou, Li-Guang;  Liu, Wei-Ping;  Zhu, Hua-Jie;  Ye, Qing-Song;  Chen, Xi-Zhu;  Gao, Wen-Gui;  Hou, Shu-Qian
Adobe PDF(432Kb)  |  收藏  |  浏览/下载：1034/284  |  提交时间：2011/12/19
Lipophilic  Platinum(Ii) Complexes  Antitumor Activity  3  5-diisopropylsalicylic Acid  
3D-QSAR and docking studies of aminopyridine carboxamide inhibitors of c-Jun N-terminal kinase-1 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 卷号: 43, 期号: 3, 页码: 604-613
作者:  Yi, Ping;  Qiu, Minghua
Adobe PDF(2801Kb)  |  收藏  |  浏览/下载：302/161  |  提交时间：2011/11/24
3d-qsar  Gold  Comfa  C-jun N-terminal Kinase-1  
Natural biflavones as novel inhibitors of cathepsin B and K 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2006, 卷号: 41, 期号: 11, 页码: 1247-1252
作者:  Zeng, G. -Z.;  Pan, X. -L.;  Tan, N. -H.;  Xiong, J.;  Zhang, Y. M.
Adobe PDF(604Kb)  |  收藏  |  浏览/下载：343/148  |  提交时间：2011/11/24
Biflavones  Inhibitors  Cathepsin b  Cathepsin k  Docking