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Discovery of novel wee1 inhibitors via structure-based virtual screening and biological evaluation 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2018, 卷号: 32, 期号: 9, 页码: 901-915
作者:  Li, Yaping;  Pu, Yinglan;  Liu, Hui;  Zhang, Li;  Liu, Xingyong;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载：428/0  |  提交时间：2018/11/06
Wee1 inhibitors  Pharmacophore model  Molecular docking  Virtual screening  Molecular dynamics simulation  
Research Progress of Polycyclic Polyprenylated Acylphloroglucinols 期刊论文
CHEMICAL REVIEWS, 2018, 卷号: 118, 期号: 7, 页码: 3508-3558
作者:  Yang, Xing-Wei;  Grossman, Robert B.;  Xu, Gang
浏览  |  Adobe PDF(27097Kb)  |  收藏  |  浏览/下载：562/113  |  提交时间：2018/05/08
Rubipodanones A-D, naphthohydroquinone dimers from rhizomes of &ITRubia podantha &IT 期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 145, 页码: 153-160
作者:  Wang, Zhe;  Zhao, Si-Meng;  Hu, Yan-Yun;  Feng, Li;  Zhao, Li-Mei;  Di, Ying-Tong;  Tan, Ning-Hua
Adobe PDF(1384Kb)  |  收藏  |  浏览/下载：252/53  |  提交时间：2018/05/08
Rubia Podantha  Rubiaceae  Naphthohydroquinone Dimers  Rubipodanones A-d  Cytotoxicity  Nf-kappa b Signaling Pathway  
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
收藏  |  浏览/下载：221/0  |  提交时间：2018/07/16
Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC