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The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
Adobe PDF(4461Kb)  |  收藏  |  浏览/下载：231/68  |  提交时间：2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Oligosaccharides from depolymerized fucosylated glycosaminoglycan: Structures and minimum size for intrinsic factor Xase complex inhibition 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 36, 页码: 14089-14099
作者:  Yin, Ronghua;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Zhao, Longyan;  Shang, Feineng;  Wu, Mingyi;  Zhao, Jinhua
Adobe PDF(1313Kb)  |  收藏  |  浏览/下载：218/32  |  提交时间：2018/10/07
Natural Product  Carbohydrate Chemistry  Carbohydrate Structure  Chemical Modification  Drug Discovery  Oligosaccharide  Thrombosis  
Structure and Function of the PriC DNA Replication Restart Protein 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 35, 页码: 18384-18396
作者:  Wessel, Sarah R.;  Cornilescu, Claudia C.;  Cornilescu, Gabriel;  Metz, Alice;  Leroux, Maxime;  Hu, Kaifeng;  Sandler, Steven J.;  Markley, John L.;  Keck, James L.
Adobe PDF(21213Kb)  |  收藏  |  浏览/下载：211/37  |  提交时间：2016/11/04
Dna Helicase  Dna Replication  Dna-protein Interaction  Nuclear Magnetic Resonance (Nmr)  Protein-protein Interaction  Dna Replication Restart  Dnab Helicase  Pric  Single-stranded Dna-binding Protein  
Natural Diterpenoid Compound Elevates Expression of Bim Protein, Which Interacts with Antiapoptotic Protein Bcl-2, Converting It to Proapoptotic Bax-like Molecule 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 卷号: 287, 期号: 2, 页码: 1054-1065
作者:  Zhao, Lixia;  He, Feng;  Liu, Haiyang;  Zhu, Yushan;  Tian, Weili;  Gao, Ping;  He, Hongping;  Yue, Wen;  Lei, Xiaobo;  Ni, Biyun;  Wang, Xiaohui;  Jin, Haijing;  Hao, Xiaojiang;  Lin, Jialing;  Chen, Quan
Adobe PDF(2908Kb)  |  收藏  |  浏览/下载：198/43  |  提交时间：2015/06/17
Baicalin, a Flavone, Induces the Differentiation of Cultured Osteoblasts AN ACTION VIA THE Wnt/beta-CATENIN SIGNALING PATHWAY 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 卷号: 286, 期号: 32, 页码: 27882-27893
作者:  Guo, Ava J. Y.;  Choi, Roy C. Y.;  Cheung, Anna W. H.;  Chen, Vicky P.;  Xu, Sherry L.;  Dong, Tina T. X.;  Chen, Ji J.;  Tsim, Karl W. K.
浏览  |  Adobe PDF(3035Kb)  |  收藏  |  浏览/下载：236/51  |  提交时间：2012/07/25
Hormone-replacement Therapy  Bone Loss  Postmenopausal Osteoporosis  Scutellaria-baicalensis  Heme Oxygenase-1  Gene-expression  Protein  Osteoprotegerin  Genistein  Cells  
Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 卷号: 284, 期号: 16, 页码: 10672-10683
作者:  Wang, Conan K.;  Hu, Shu-Hong;  Martin, Jennifer L.;  Sjogren, Tove;  Hajdu, Janos;  Bohlin, Lars;  Claeson, Per;  Goransson, Ulf;  Rosengren, K. Johan;  Tang, Jun;  Tan, Ning-Hua;  Craik, David J.
Adobe PDF(762Kb)  |  收藏  |  浏览/下载：222/65  |  提交时间：2012/03/21
Ligusticum Chuanxiong  4-pentylcyclohex-3-ene-1 Alpha  Phthalide Derivatives  2 Beta-diol  Ligusticoside a  Wallichii  Phthalides  Constituents  Derivatives  Rhizomes  Dimers