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FPR2-based anti-inflammatory and anti-lipogenesis activities of novel meroterpenoid dimers from Ganoderma 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105338
作者:  Peng,Xing-Rong;  Wang,Qian;  Wang,Hui-Rong;  Hu,Kun;  Xiong,Wen-Yong;  Qiu,Ming-Hua
浏览  |  Adobe PDF(7004Kb)  |  收藏  |  浏览/下载:142/28  |  提交时间:2022/04/02
Ganoderma applanatum  Meroterpenoid dimers  Molecular docking  Anti-lipogenesis  FPR2-based inflammation  INDUCED INSULIN-RESISTANCE  ADIPOCYTE DIFFERENTIATION  OBESITY  INFLAMMATION  DEFICIENCY  MACROPHAGES  ACTIVATION  EXPRESSION  LIGAND  MICE  
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
浏览  |  Adobe PDF(3665Kb)  |  收藏  |  浏览/下载:115/19  |  提交时间:2022/04/02
Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN  
Green tea (Camellia sinensis) aqueous extract alleviates postmenopausal osteoporosis in ovariectomized rats and prevents RANKL-induced osteoclastogenesis in vitro 期刊论文
FOOD & NUTRITION RESEARCH, 2018, 卷号: 62, 页码: 11
作者:  Wu, Xin;  Xie, Chuan-qi;  Zhu, Qiang-qiang;  Wang, Ming-yue;  Sun, Bin;  Huang, Yan-ping;  Shen, Chang;  An, Meng-Fei;  Zhao, Yun-li;  Wang, Xuan-jun;  Sheng, Jun
收藏  |  浏览/下载:243/0  |  提交时间:2018/11/12
green tea aqueous extract  osteoporosis  ovariectomy  receptor activator of the nuclear factor kappa B ligand  osteoclast  
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice 期刊论文
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:  Feng, Li;  Luo, Huan;  Xu, Zhijian;  Yang, Zhuo;  Du, Guoxin;  Zhang, Yu;  Yu, Lijing;  Hu, Kaifeng;  Zhu, Weiliang;  Tong, Qingchun;  Chen, Kaixian;  Guo, Fujiang;  Huang, Cheng;  Li, Yiming
浏览  |  Adobe PDF(841Kb)  |  收藏  |  浏览/下载:305/117  |  提交时间:2016/08/22
Alternative Binding Site  Bavachinin  Canonical Ligand-binding Pocket  Carbohydrate Metabolism  Lipid Metabolism  Pan-ppar Agonist  Synergistic Effects  
Synthesis, crystal structures and catalytic activity of tetrakis(acetato)dirhodium(II) complexes with axial picoline ligands 期刊论文
INORGANICA CHIMICA ACTA, 2015, 卷号: 434, 页码: 113-120
作者:  Ye,Qing-Song;  Li,Xiao-Nian;  Jin,Yi;  Yu,Juan;  Chang,Qiao-Wen;  Jiang,Jing;  Yan,Cai-Xian;  Li,Jie;  Liu,Wei-Ping
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Rhodium  Acetate  Picoline  Catalytic Activity  C-h Center Dot Center Dot Center Dot o Hydrogen Bond  Axial Ligand  Acetate  Carboxylates  Binding  Adduct  Bonds  Units  Dna  
Addition of aldehydes with allyltrichlorosilane catalyzed by chiral bis-N-O secondary amides 期刊论文
TETRAHEDRON, 2013, 卷号: 69, 期号: 48, 页码: 10431-10437
作者:  Deng, Yu;  Pan, Wei;  Pei, Yu-Ning;  Li, Jin-Liang;  Bai, Bing;  Zhu, Hua-Jie
浏览  |  Adobe PDF(869Kb)  |  收藏  |  浏览/下载:742/147  |  提交时间:2014/01/21
Bis-n-o Amides  Allylation  L-tryptophan  Axial Ligand  
Introduction of aromatic group on 4 '-OH of alpha-GalCer manipulated NKT cell cytokine production 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 卷号: 19, 期号: 8, 页码: 2767-2776
作者:  Zhang, Wenpeng;  Xia, Chengfeng;  Nadas, Janos;  Chen, Wenlan;  Gu, Li;  Wang, Peng George
Adobe PDF(1366Kb)  |  收藏  |  浏览/下载:362/93  |  提交时间:2012/04/10
Alpha-galcer  Nkt Cell Ligand  Computer Modeling  Cd1d  Nkt Tcr  
Introduction of aromatic group on 40-OH of a-GalCer manipulated NKTcell cytokine production 期刊论文
Bioorganic & Medicinal Chemistry, 2011, 卷号: 19, 期号: 0, 页码: 2767–2776
作者:  Wenpeng Zhang;  Chengfeng Xia;  Janos Nadas;  Wenlan Chen;  Li Gua;  Peng George Wang
Adobe PDF(1366Kb)  |  收藏  |  浏览/下载:94/2  |  提交时间:2017/07/24
A-galcer  Nkt Cell Ligand  Computer Modeling  Cd1d  Nkt Tcr