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Compositional and phylogenetic beta diversity reveal different patterns of aquatic plant assemblages in lakes along the Changjiang River 期刊论文
AQUATIC BOTANY, 2023, 卷号: 186, 页码: 103630
作者:  Li,Xinhui;  Wang,Dandan;  Li,Heng
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Aquatic plants  Changjiang River  Compositional beta diversity  Phylogenetic beta diversity  River capture  CYTOCHROME-B  EVOLUTION  DIVERSIFICATION  BIOGEOGRAPHY  ENDEMISM  SYSTEM  FOREST  CHINA  LINE  ASIA  
Effects of drainage reorganization on phytogeographic pattern in Sino-Himalaya 期刊论文
ALPINE BOTANY, 2022, 卷号: 132, 期号: 1, 页码: 141-151
作者:  Sun,Hang;  Li,Zhimin;  Landis,Jacob B.;  Qian,Lishen;  Zhang,Ticao;  Deng,Tao
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Sino-Himalaya  Paleo Red River  Valley plants  Drainage reorganization  Biogeographic evolution  TERMINALIA-FRANCHETII COMBRETACEAE  MEKONG-SALWEEN DIVIDE  TANAKA-KAIYONG LINE  RIVER-CAPTURE  HENGDUAN MOUNTAINS  GENETIC-STRUCTURE  SOUTHWEST CHINA  CYTOCHROME-B  PHYLOGEOGRAPHY  EVOLUTION  
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
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One Of The Major compOnents Isolated From The Traditional  2-methyl-1  Chinese Medicine Rubia Yunnanensis  3  Exhibited Inhibitory Activity On The proliferatiOn Of Several  6-trihydroxy-9  HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay  10-anthraquinone (Mta)  And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle  Arrest In Human Cervical carcInoma Hela Cells. Further  Mta Was Found To Induce apopTosis Of Hela Cells  Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And  Release Of Cytochrome c Into The Cytosol  Which Caused The Cleavage Of Caspase And Poly(Adp-ribose)  Polymerase And Finally Triggered The Apoptosis. furThermore  The P53/p21/cdc2-cyclin B1 Signaling Was  Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of  Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused  The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of  R. Yunnanensis  a Folk Anti-cancer Herb Used In Yunnan  China.