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Sesquiterpenoids from Alpinia oxyphylla with GLP-1 Stimulative Effects through Ca2+/CaMKII and PKA Pathways and Multiple-Enzyme Inhibition 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 43, 页码: 16148-16159
作者:  Cui,Can;  Wu,Sheng-Li;  Chen,Ji-Jun;  Gongpan,Pianchou;  Guan,Min;  Geng,Chang-An
浏览  |  Adobe PDF(2550Kb)  |  收藏  |  浏览/下载：61/10  |  提交时间：2024/07/10
Alpinia oxyphylla  sesquiterpenoids  GLP-1 stimulation  Ca2+/CaMKII and PKA pathways  alpha-glucosidase and PTP1B inhibitory activity  
Design, Synthesis, and Evaluation of the COX-2 Inhibitory Activities of New 1,3-Dihydro-2H-indolin-2-one Derivatives 期刊论文
MOLECULES, 2023, 卷号: 28, 期号: 12, 页码: 4668
作者:  Pan,Taohua;  He,Maofei;  Deng,Lulu;  Li,Jiang;  Fan,Yanhua;  Hao,Xiaojiang;  Mu,Shuzhen
浏览  |  Adobe PDF(3057Kb)  |  收藏  |  浏览/下载：68/13  |  提交时间：2024/05/09
oxindoles  alpha,beta-unsaturated ketone  anti-inflammatory  COX-2 inhibitory activity  ANTIINFLAMMATORY ACTIVITY  NATURAL-PRODUCTS  OXINDOLE-DERIVATIVES  NITRIC-OXIDE  POTENT  CYCLOOXYGENASE-2  DISCOVERY  PAIN  LIABILITY  
Recent Studies on Protective Effects of Walnuts against Neuroinflammation 期刊论文
NUTRIENTS, 2022, 卷号: 14, 期号: 20, 页码: 4360
作者:  Tan, Bing;  Wang, Yuxi;  Zhang, Xudong;  Sun, Xiangjun
浏览  |  Adobe PDF(999Kb)  |  收藏  |  浏览/下载：121/14  |  提交时间：2024/04/30
walnuts  neuroinflammation  neurodegenerative diseases  oxidative stress  antioxidant activity  gut microbes  ALPHA-LINOLENIC ACID  BETA-AMYLOID PROTEIN  NF-KAPPA-B  OXIDATIVE STRESS  COGNITIVE IMPAIRMENT  MEDITERRANEAN DIET  INDUCED ACTIVATION  BV-2 MICROGLIA  ELLAGIC ACID  GALLIC ACID  
The Antioxidant Properties of Mushroom Polysaccharides can Potentially Mitigate Oxidative Stress, Beta-Cell Dysfunction and Insulin Resistance 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 874474
作者:  Arunachalam, Karuppusamy;  Sreeja, Puthanpura Sasidharan;  Yang, Xuefei
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reactive oxygen species  oxidative stress  antioxidant  diabetes mellitus  mushroom polysaccharides  AGARICUS-BLAZEI MURILL  GANODERMA-LUCIDUM POLYSACCHARIDES  ACTIVATED SIGNALING PATHWAYS  TYPE-2 DIABETES-MELLITUS  PROTEIN-KINASE-C  MT-ALPHA-GLUCAN  MEDICINAL MUSHROOM  SUBMERGED-CULTURE  PHELLINUS-LINTEUS  STRUCTURAL-CHARACTERIZATION  
In vitro assessment of the glucose-lowering effects of berberrubine-9-O-beta-D-glucuronide, an active metabolite of berberrubine 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 3, 页码: 351-361
作者:  Yang, Na;  Sun, Run-Bin;  Chen, Xing-Long;  Zhen, Le;  Ge, Chun;  Zhao, Yu-Qing;  He, Jun;  Geng, Jian-Liang;  Guo, Jia-Hua;  Yu, Xiao-Yi;  Fei, Fei;  Feng, Si-Qi;  Zhu, Xuan-Xuan;  Wang, Hong-Bo;  Fu, Feng-Hua;  Aa, Ji-Ye;  Wang, Guang-Ji
浏览  |  Adobe PDF(4661Kb)  |  收藏  |  浏览/下载：301/101  |  提交时间：2017/05/19
Hyperglycemia  Glucose-lowering Effect  Berberine  Berberrubine  Glucuronide  Alpha-glycosidase  Hfd-induced Hyperglycemia Model Of C57bl/6 Mice  Human Normal Liver Cell Line L-o2  Pharmacokinetics  
Monoterpenoid Indole Alkaloids from Catharanthus roseus Cultivated in Yunnan 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2015, 卷号: 10, 期号: 12, 页码: 2085-2086
作者:  Wang, Bei;  Liu, Lu;  Chen, Ying-Ying;  Li, Qiong;  Li, Dan;  Liu, Ya-Ping;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1097Kb)  |  收藏  |  浏览/下载：204/29  |  提交时间：2016/05/04
Catharanthus Roseus  Apocynaceae  Monoterpenoid Indole Alkaloids  15  20-dehydro-3 Alpha-(2-oxopropyl) Coronaridine  
A new Amaryllidaceae alkaloid from the bulbs of Lycoris radiata 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2013, 卷号: 11, 期号: 4, 页码: 406-410
作者:  Huang Sheng-Dian;  Zhang Yu;  He Hong-Ping;  Li Shi-Fei;  Tang Gui-Hua;  Chen Duo-Zhi;  Cao Ming-Ming;  Di Ying-Tong;  Hao Xiao-Jiang
浏览  |  Adobe PDF(606Kb)  |  收藏  |  浏览/下载：320/69  |  提交时间：2013/10/16
Lycoris Radiata  Amaryllidaceae Alkaloids  Homolycorine-type  2 Alpha-methoxy-6-o-methyloduline  2 Alpha-methoxy-6-beta-ethyloduline  
A new eudesmane sesquiterpenoid lactone from Chloranthus japonicus 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2012, 卷号: 10, 期号: 1, 页码: 24-27
作者:  Fang Ping-Lei;  Liu Hai-Yang;  Zhong Hui-Min
Adobe PDF(285Kb)  |  收藏  |  浏览/下载：378/91  |  提交时间：2012/06/07
Acute Promyelocytic Leukemia  Activated Protein-kinase  Retinoic Acid  Signal-transduction  Alpha Oncoprotein  Pmlrar-alpha  C/ebp-beta  Product  Stress  H2o2  
Four new compounds from the basidiomycete Craterellus odoratus 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2012, 卷号: 14, 期号: 10, 页码: 950-955
作者:  Guo, Hua;  Feng, Tao;  Li, Zheng-Hui;  Liu, Ji-Kai
浏览  |  Adobe PDF(238Kb)  |  收藏  |  浏览/下载：199/59  |  提交时间：2015/06/17
Craterellus Odoratus  Craterellin d  5-hydroxymethyl-2-hydroxy-4-methoxy-phenylethanone  6 Alpha-hydroxy-3-methoxy-4 Alpha-methyl-2-cyclohexen-1-one  5-carboxyl-2-[2-(1  2-dihydroxyisopropyl)]-benzofuran  
Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 卷号: 284, 期号: 16, 页码: 10672-10683
作者:  Wang, Conan K.;  Hu, Shu-Hong;  Martin, Jennifer L.;  Sjogren, Tove;  Hajdu, Janos;  Bohlin, Lars;  Claeson, Per;  Goransson, Ulf;  Rosengren, K. Johan;  Tang, Jun;  Tan, Ning-Hua;  Craik, David J.
Adobe PDF(762Kb)  |  收藏  |  浏览/下载：274/81  |  提交时间：2012/03/21
Ligusticum Chuanxiong  4-pentylcyclohex-3-ene-1 Alpha  Phthalide Derivatives  2 Beta-diol  Ligusticoside a  Wallichii  Phthalides  Constituents  Derivatives  Rhizomes  Dimers