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Deciphering fungal metabolon coupling tandem inverse-electron-demand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids 期刊论文
SCIENCE CHINA-CHEMISTRY, 2025, 卷号: 68, 期号: 1, 页码: 288-296
作者:  Liu, Shuai;  Xu, Wen-Qiang;  Di, Ying-Tong;  Tang, Man-Cheng;  Chen, Ding-Kang;  Cao, Ming-Ming;  Chang, Yao-Wen;  Tang, Hong-Yu;  Yuan, Chun-Mao;  Yang, Jun-Bo;  Zuo, Zhi-Li;  Guo, Han;  Xu, Zi-Fei;  Zeng, Ying;  Wu, Yun-Dong;  Hao, Xiao-Jiang
Adobe PDF(1777Kb)  |  收藏  |  浏览/下载：0/0  |  提交时间：2025/10/20
Oligosaccharide-assisted resolution of holothurian fucosylated chondroitin sulfate for fine structure and P-selectin inhibition 期刊论文
CARBOHYDRATE POLYMERS, 2025, 卷号: 351, 页码: 123145
作者:  Pan, Ying;  Sun, Huifang;  Gu, Xi;  Li, Sujuan;  Yang, Shengtao;  Zhang, Liang;  Mao, Hui;  Wang, Pin;  Yang, Shasha;  Yin, Ronghua;  Zuo, Zhili;  Zhao, Jinhua
Adobe PDF(7292Kb)  |  收藏  |  浏览/下载：0/0  |  提交时间：2025/10/20
Identification of novel GSPT1 degraders by virtual screening and bioassay 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 273, 页码: 116524
作者:  Zhang, Shuqun;  Nie, Shiyun;  Ma, Guangchao;  Shen, Meiling;  Kong, Lingmei;  Zuo, Zhili;  Li, Yan
Adobe PDF(12264Kb)  |  收藏  |  浏览/下载：0/0  |  提交时间：2025/10/20
Structural optimization and bioactivity evaluation of 2-(Methylcarbonylamino) thiazole derivatives as novel PDE4B inhibitors 期刊论文
TETRAHEDRON, 2024, 卷号: 167, 页码: 134250
作者:  Ma, Rui;  Song, Na;  Gu, Xi;  Guo, Rong;  Shen, Meiling;  Zhang, Shuqun;  Yang, Weimin;  Zuo, Zhili
浏览  |  Adobe PDF(11203Kb)  |  收藏  |  浏览/下载：0/0  |  提交时间：2025/10/20
Phylogenomic insights into the reticulate evolution of Camellia sect. Paracamellia Sealy (Theaceae) 期刊论文
JOURNAL OF SYSTEMATICS AND EVOLUTION, 2023
作者:  Qin,Sheng-Yuan;  Chen,Kai;  Zhang,Wen-Ju;  Xiang,Xiao-Guo;  Zuo,Zheng-Yu;  Guo,Cen;  Zhao,Yao;  Li,Lin-Feng;  Wang,Yu-Guo;  Song,Zhi-Ping;  Yang,Ji;  Yang,Xiao-Qiang;  Zhang,Jian;  Jin,Wei-Tao;  Wen,Qiang;  Zhao,Song-Zi;  Chen,Jia-Kuan;  Li,De-Zhu;  Rong,Jun
浏览  |  Adobe PDF(2146Kb)  |  收藏  |  浏览/下载：589/277  |  提交时间：2024/07/10
Camellia oleifera  hybridization  phylogenomics  plastome  polyploidization  transcriptome  EVERGREEN BROADLEAVED FORESTS  HISTORY  DYNAMICS  OLEIFERA  CHINA  PHYLOGEOGRAPHY  ALIGNMENT  TREE  
Phylogenomic insights into the origin and evolutionary history of evergreen broadleaved forests in East Asia under Cenozoic climate change 期刊论文
MOLECULAR ECOLOGY, 2023, 卷号: 32, 期号: 11, 页码: 2850-2868
作者:  Qin,Sheng-Yuan;  Zuo,Zheng-Yu;  Guo,Cen;  Du,Xin-Yu;  Liu,Shui-Yin;  Yu,Xiang-Qin;  Xiang,Xiao-Guo;  Rong,Jun;  Liu,Bing;  Liu,Zhi-Fang;  Ma,Peng-Fei;  Li,De-Zhu
浏览  |  Adobe PDF(12802Kb)  |  收藏  |  浏览/下载：649/297  |  提交时间：2024/07/10
East Asian monsoon  evergreen broadleaved forests  genome resequencing  Lauraceae  Litsea complex  single-nucleotide variants  SOUTHERN CHINA EVIDENCE  NORTHERN-HEMISPHERE  MOLECULAR PHYLOGENY  SPECIES RICHNESS  LITSEA COMPLEX  R PACKAGE  LAURACEAE  EOCENE  TERTIARY  BIOGEOGRAPHY  
Discovery of potential novel TRPC5 inhibitors by virtual screening and bioassay 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 94, 页码: 117477
作者:  Shen,Meiling;  Li,Lingfeng;  Li,Yue;  Gu,Xi;  Bai,Longhui;  Xia,Chengfeng;  Xiong,Wenyong;  Zuo,Zhili
Adobe PDF(6089Kb)  |  收藏  |  浏览/下载：824/512  |  提交时间：2024/07/22
TRPC5  Inhibitors  Virtual screening  Ca 2+channel  CHANNELS  IDENTIFICATION  PERMEABILITY  CALCIUM  
Discovery of 2-(Methylcarbonylamino) thiazole as PDE4 inhibitors via virtual screening and biological evaluation 期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 124, 页码: 108567
作者:  Ma,Rui;  Song,Na;  Wang,Lveli;  Gu,Xi;  Xiong,Feng;  Zhang,Shuqun;  Zhang,Jie;  Yang,Weimin;  Zuo,Zhili
Adobe PDF(5778Kb)  |  收藏  |  浏览/下载：521/365  |  提交时间：2024/07/22
PHOSPHODIESTERASE-4 INHIBITOR  ACCURATE DOCKING  APREMILAST  EFFICACY  INSIGHTS  DISEASE  ASTHMA  POTENT  GLIDE  
Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin;  Zuo,Zhili
Adobe PDF(5035Kb)  |  收藏  |  浏览/下载：524/305  |  提交时间：2024/07/22
Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION  
Small-Molecule Drugs in Immunotherapy 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 13, 页码: 1341-1359
作者:  Hao,Xuanrun;  Chen,Zhongliang;  Li,Haining;  Wei,Minqin;  Zuo,Zhili;  Su,Qing
Adobe PDF(29350Kb)  |  收藏  |  浏览/下载：161/39  |  提交时间：2024/07/25
Cancer immunotherapy  inhibitors  Pd-1/Pd-L1 inhibitor  IDO inhibitor  STING agonists  ROR gamma t agonists  TGF  beta inhibitors  INDOLEAMINE 2,3-DIOXYGENASE  SIGNALING INHIBITOR  DENDRITIC CELLS  GROWTH  TUMOR  PATHWAY  PEMBROLIZUMAB  RECEPTORS  DISCOVERY  VADIMEZAN