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Utilizing artificial intelligence for precision exploration of N protein targeting phenanthridine sars-cov-2 inhibitors: A novel approach 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 279, 页码: 116885
作者:  Xiang, Zheng-rui;  Fan, Shi-rui;  Ren, Juan;  Ruan, Ting;  Chen, Yuan;  Zhang, Yun-wu;  Wang, Yi-ting;  Yu, Ze-zhou;  Wang, Chao-fan;  Sun, Xiao-long;  Hao, Xiao-Jiang;  Chen, Duo-Zhi
浏览  |  Adobe PDF(8080Kb)  |  收藏  |  浏览/下载：9/2  |  提交时间：2025/10/20
New resorcylic acid derivatives of Lysimachia tengyuehensis against MRSA and VRE by interfering with bacterial metabolic imbalance 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 277, 页码: 116714
作者:  Shi, Nian;  Wang, Zhao-Jie;  Shi, Yang-Zhu;  Jiang, Ling;  Zhu, Yan-Yan;  He, Xing-Chao;  Zhou, Zhong-Shun;  Wei, Mei-Zhen;  Zhao, Yun-Li;  Luo, Xiao-Dong
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Oleanolic acid derivatives against drug-resistant bacteria and fungi by multi-targets to avoid drug resistance 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 280, 页码: 116940
作者:  Wei, Mei-Zhen;  Wang, Zhao-Jie;  Zhu, Yan-Yan;  Zu, Wen-Biao;  Zhao, Yun-Li;  Luo, Xiao-Dong
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Development of α-Helical Antimicrobial Peptides with Imperfect Amphipathicity for Superior Activity and Selectivity 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 21, 页码: 19561-19572
作者:  Wu, Zhongxiang;  Cai, Ying;  Han, Yajun;  Su, Yunhan;  Zhang, Tianyu;  Wang, Xingyu;  Yan, An;  Wang, Liunan;  Wu, Sijing;  Wang, Gan;  Zhang, Zhiye
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Structure optimizing of flavonoids against both MRSA and VRE 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 271, 页码: 116401
作者:  Wei, Mei-Zhen;  Zhu, Yan-Yan;  Zu, Wen-Biao;  Wang, Huan;  Bai, Li -Yu;  Zhou, Zhong-Shun;  Zhao, Yun-Li;  Wang, Zhao-Jie;  Luo, Xiao-Dong
浏览  |  Adobe PDF(10942Kb)  |  收藏  |  浏览/下载：6/5  |  提交时间：2025/10/20
Identification of novel GSPT1 degraders by virtual screening and bioassay 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 273, 页码: 116524
作者:  Zhang, Shuqun;  Nie, Shiyun;  Ma, Guangchao;  Shen, Meiling;  Kong, Lingmei;  Zuo, Zhili;  Li, Yan
浏览  |  Adobe PDF(12264Kb)  |  收藏  |  浏览/下载：7/3  |  提交时间：2025/10/20
Synthesis and antihepatoma activity of guaianolide dimers derived from lavandiolide I 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 104, 页码: 129708
作者:  Wang, Xing;  Li, Tian-Ze;  Ma, Yun-Bao;  Ma, Wen-Jing;  Xue, Dong;  Chen, Ji-Jun
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Leucosceptrane Sesterterpenoids as a New Type of Natural Immunosuppressive Agents in Treating Sepsis 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 67, 期号: 1, 页码: 513-528
作者:  Guo,Kai;  Zhou,Ting-Ting;  Luo,Shi-Hong;  Liu,Yan-Chun;  Liu,Yan;  Li,Sheng-Hong
浏览  |  Adobe PDF(12263Kb)  |  收藏  |  浏览/下载：794/485  |  提交时间：2024/07/10
GLANDULAR TRICHOMES  PRODUCTS  HARBOR  CANUM  
Discovery of potential novel TRPC5 inhibitors by virtual screening and bioassay 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 94, 页码: 117477
作者:  Shen,Meiling;  Li,Lingfeng;  Li,Yue;  Gu,Xi;  Bai,Longhui;  Xia,Chengfeng;  Xiong,Wenyong;  Zuo,Zhili
浏览  |  Adobe PDF(6089Kb)  |  收藏  |  浏览/下载：928/537  |  提交时间：2024/07/22
TRPC5  Inhibitors  Virtual screening  Ca 2+channel  CHANNELS  IDENTIFICATION  PERMEABILITY  CALCIUM  
Development of actein derivatives as potent anti-triple negative breast cancer agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 89, 页码: 129307
作者:  Zhang,Honglin;  Chen,Yiyan;  Huang,Songwen;  Xiao,Wen-Wen;  Qiu,Ming-Hua;  Shao,Li-Dong;  Chen,Chuan-Huizi;  Li,Dashan
浏览  |  Adobe PDF(1187Kb)  |  收藏  |  浏览/下载：301/55  |  提交时间：2024/07/22
Actein  Modification  Triple negative breast cancer  Structure-activity relationships  Mechanism  GROWTH-INHIBITORY ACTIVITY  BLACK COHOSH  EXTRACTS