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Discovery of potential novel TRPC5 inhibitors by virtual screening and bioassay 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 94, 页码: 117477
作者:  Shen,Meiling;  Li,Lingfeng;  Li,Yue;  Gu,Xi;  Bai,Longhui;  Xia,Chengfeng;  Xiong,Wenyong;  Zuo,Zhili
Adobe PDF(6089Kb)  |  收藏  |  浏览/下载：145/25  |  提交时间：2024/07/22
TRPC5  Inhibitors  Virtual screening  Ca 2+channel  CHANNELS  IDENTIFICATION  PERMEABILITY  CALCIUM  
Development of actein derivatives as potent anti-triple negative breast cancer agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 89, 页码: 129307
作者:  Zhang,Honglin;  Chen,Yiyan;  Huang,Songwen;  Xiao,Wen-Wen;  Qiu,Ming-Hua;  Shao,Li-Dong;  Chen,Chuan-Huizi;  Li,Dashan
Adobe PDF(1187Kb)  |  收藏  |  浏览/下载：126/18  |  提交时间：2024/07/22
Actein  Modification  Triple negative breast cancer  Structure-activity relationships  Mechanism  GROWTH-INHIBITORY ACTIVITY  BLACK COHOSH  EXTRACTS  
Discovery of diverse sesquiterpenoids from Magnolia grandiflora with cytotoxic activities by inducing cell apoptosis 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 106707
作者:  Xu,Shuangyu;  Tang,Yunyan;  Li,Yanan;  Yang,Jue;  Gu,Wei;  Hao,Xiaojiang;  Yuan,Chunmao
Adobe PDF(5040Kb)  |  收藏  |  浏览/下载：150/30  |  提交时间：2024/07/22
Magnolia grandiflora  Sesquiterpenoids  Isolation and structural modification  Cytotoxic activity  Apoptosis  LACTONES  DERIVATIVES  LEAVES  AGENTS  
Design, synthesis, and biological evaluation of artemyrianolide H derivatives as potential antihepatoma agents 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 137, 页码: 106617
作者:  Li,Tian-Ze;  Yang,Xiao-Tong;  Ma,Wen-Jing;  Ma,Yun-Bao;  Li,Feng-Jiao;  Wang,Yong-Cui;  Chen,Ji-Jun
Adobe PDF(9670Kb)  |  收藏  |  浏览/下载：145/31  |  提交时间：2024/07/22
Artemyrianolide H  Germacranolide derivatives  Antihepatoma activity  Apoptosis  DIMERS  
11,12-seco-Abietane-type diterpene lactones with potential antiplatelet activity from Salvia prattii 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 106834
作者:  Xia,Fan;  Lin,Li-Sha;  Ye,Yan-Song;  Yang,Lian;  Zhao,Jin-Hua;  Xu,Gang
Adobe PDF(2360Kb)  |  收藏  |  浏览/下载：121/30  |  提交时间：2024/07/22
Salvia prattii  11  12  seco -Abietane-type diterpenes  Antiplatelet activity  
Oligomeric phloroglucinols with hAChE inhibitory and antibacterial activities from tropic Rhodomyrtus tomentosa 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 106836
作者:  Luo,E-E;  Liu,Si-Na;  Wang,Zhao-Jie;  Chen,Ling-Yun;  Liang,Cheng-Qin;  Yu,Mu-Yuan;  Qin,Xu-Jie
浏览  |  Adobe PDF(3972Kb)  |  收藏  |  浏览/下载：116/18  |  提交时间：2024/07/22
Rhodomyrtus tomentosa  Oligomeric phloroglucinols  h AChE inhibitors  Molecular docking  Antibacterial effects  MYRTUCOMMULONE  DERIVATIVES  ACYLPHLOROGLUCINOLS  MYRTUCOMMUACETALONE  LEAVES  
Pegriseofamines A-E: Five cyclopiazonic acid related indole alkaloids from the fungus Penicillium griseofulvum 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 136, 页码: 106553
作者:  Liang,Yu;  Liao,Hong;  Chen,Xuanni;  Wang,Qiwei;  Li,Qin;  Shen,Yong;  Zheng,Yuyi;  Li,Xiao-Nian;  Zhu,Hucheng;  Li,Dongyan;  Sun,Weiguang;  Chen,Chunmei;  Zhang,Yonghui
浏览  |  Adobe PDF(11018Kb)  |  收藏  |  浏览/下载：130/10  |  提交时间：2024/07/22
Penicillium griseofulvum  Alkaloid  Cyclopiazonic acid  Immunosuppression activity  
Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin;  Zuo,Zhili
浏览  |  Adobe PDF(5035Kb)  |  收藏  |  浏览/下载：152/26  |  提交时间：2024/07/22
Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION  
Cytotoxic C-20 non-oxygenated ent-kaurane diterpenoids from Isodon wardii 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106512
作者:  Tan,Qian;  Hu,Kun;  Li,Xiao-Nian;  Yang,Xing-Zhi;  Sun,Han-Dong;  Puno,Pema-Tenzin
Adobe PDF(3171Kb)  |  收藏  |  浏览/下载：191/37  |  提交时间：2024/07/22
Isodon wardii  ent-Kauranoids  Cytotoxicity  Apoptosis  Cell cycle  
Isolation and identification of hemostatic steroidal glycosides from Ypsilandra thibetica 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 106268
作者:  Ma,Wen-Yi;  Xie,Jing;  Yu,Ling-Ling;  Zhang,Shi-Juan;  Ni,Wei;  Yan,Huan;  Liu,Hai-Yang
Adobe PDF(2307Kb)  |  收藏  |  浏览/下载：128/24  |  提交时间：2024/07/22
Ypsilandra thibetica  Steroidal saponins  Ypsilandrosides Z1-Z14  Hemostatic activity  Structure-activity relationship  SPIROSTANE GLYCOSIDES  NMR-SPECTROSCOPY  AGGREGATION  SAPOGENINS  SAPONINS