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Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 10, 页码: 2353-2359
作者:  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhao, Yong;  Wang, Li-Jun;  Guo, Rui-Hua;  Liang, Wen-Juan;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(3861Kb)  |  收藏  |  浏览/下载：305/73  |  提交时间：2014/06/23
Anti-hbv Activity  DehydroAndrographolide And  Andrographolide Derivatives  Structure-activity Relationships  Octanol-water Partition Coefficients  
(+/-)-Paeoveitol, a Pair of New Norditerpene Enantiomers from Paeonia veitchii 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 2, 页码: 424-427
作者:  Liang, Wen-Juan;  Geng, Chang-An;  Zhang, Xue-Mei;  Chen, Hao;  Yang, Cai-Yan;  Rong, Guang-Qing;  Zhao, Yong;  Xu, Hong-Bo;  Wang, Hao;  Zhou, Ning-Jia;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Chen, Ji-Jun
Adobe PDF(256Kb)  |  收藏  |  浏览/下载：386/136  |  提交时间：2014/04/09
Monoterpene Glycosides  Paeoniflorin  Root  
Swerpunilactones A and B, the first example of xanthone and secoiridoid heterodimers from Swertia punicea, S. hispidicalyx, and S. yunnanensis 期刊论文
TETRAHEDRON LETTERS, 2013, 卷号: 54, 期号: 21, 页码: 2710-2712
作者:  Wang, Hong-Ling;  Cao, Tuan-Wu;  Jiang, Fu-Qiang;  Geng, Chang-An;  Zhang, Xue-Mei;  Huang, Xiao-Yan;  Wang, Li-Jun;  Kang-He, Sing Wd;  Hao-Chen;  Liang, Wen-Juan;  Rong, Guang-Qing;  Chen, Ji-Jun
浏览  |  Adobe PDF(393Kb)  |  收藏  |  浏览/下载：498/140  |  提交时间：2013/06/08
Swerpunilactones A-b  Anti-hbv Activity  Swertia Punicea  Swertia Hispidicalyx  Swertia Yunnanensis  
Synthesis of hemslecin A derivatives: A new class of hepatitis B virus inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 5, 页码: 1201-1205
作者:  Guo, Rui-Hua;  Geng, Chang-An;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Quan;  Wang, Li-Jun;  Zhang, Xue-Mei;  Zhang, Rong-Ping;  Chen, Ji-Jun
浏览  |  Adobe PDF(460Kb)  |  收藏  |  浏览/下载：395/93  |  提交时间：2013/03/18
Hemslecin a  Derivatives  Hepatitis b Virus  
Design, synthesis, and molecular hybrids of caudatin and cinnamic acids as novel anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 54, 页码: 352-365
作者:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Luo, Jie;  Huang, Xiao-Yan;  Chen, Hao;  Zhou, Ning-Jia;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(719Kb)  |  收藏  |  浏览/下载：432/138  |  提交时间：2012/11/30
Synthesis  Molecular Hybrids  Caudatin Derivatives  Anti-hepatitis b Virus  Unique Mechanisms  
Three New C19-Diterpenoid Alkaloids from Aconitum transsectum 期刊论文
HELVETICA CHIMICA ACTA, 2012, 卷号: 95, 期号: 3, 页码: 509-513
作者:  Shen, Yong;  Ai, Hong-Lian;  Cao, Tuan-Wu;  Wang, Jian-Jun;  Zi, Shu-Hui;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(174Kb)  |  收藏  |  浏览/下载：373/111  |  提交时间：2012/06/07
Aconitum Transsectum  AA?-?conitramines a?-?A?-?c  Alkaloids  
Two new C-19-diterpenoid alkaloids from Aconitum transsectum 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2012, 卷号: 14, 期号: 3, 页码: 244-248
作者:  Shen, Yong;  Ai, Hong-Lian;  Zi, Shu-Hui;  Wang, Jian-Jun;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(99Kb)  |  收藏  |  浏览/下载：362/138  |  提交时间：2012/06/07
Aconitum Transsectum  Diterpenoid Alkaloids  Aconitramines d And e  
Anti-Hepatitis B Virus Active Lactones from the Traditional Chinese Herb: Swertia mileensis 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2011, 卷号: 17, 期号: 14, 页码: 3893-3903
作者:  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Luo, Jie;  Guo, Rui-Hua;  Zhou, Jun;  Shen, Yong;  Zuo, Ai-Xue;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(1108Kb)  |  收藏  |  浏览/下载：399/127  |  提交时间：2012/04/10
Antiviral Agents  Biosynthesis  Fused-ring Systems  Hepatitis b Virus  Natural Products  Swerilactones H-k  Swertia Mileensis  
Structure-activity relationships study of 6-chloro-4-(2-chlorophenyl)-3-(2-hydroxyethyl) quinolin-2(1H)-one derivatives as novel non-nucleoside anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 1, 页码: 307-319
作者:  Guo, Rui-Hua;  Zhang, Quan;  Ma, Yun-Bao;  Luo, Jie;  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Zhou, Jun;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(866Kb)  |  收藏  |  浏览/下载：358/91  |  提交时间：2012/04/10
Anti-hepatitis b Virus Activity  Quinolin-2(1h)-one  Structure-activity Relationships  
Swerilactones E-G, three unusual lactones from Swertia mileensis 期刊论文
TETRAHEDRON LETTERS, 2010, 卷号: 51, 期号: 18, 页码: 2483-2485
作者:  Geng, Chang-An;  Zhang, Xue-Mei;  Ma, Yun-Bao;  Jiang, Zhi-Yong;  Luo, Jie;  Zhou, Jun;  Wang, Hong-Ling;  Chen, Ji-Jun
Adobe PDF(414Kb)  |  收藏  |  浏览/下载：335/143  |  提交时间：2012/03/21
Swertia Mileensis  Swerilactones E-g  Secoiridoid Aglycone  Anti Hbv Activity