Swerilactones E-G, three unusual lactones from Swertia mileensis

doi:10.1016/j.tetlet.2010.02.156

	Swerilactones E-G, three unusual lactones from Swertia mileensis
	Geng, Chang-An1,2 ; Zhang, Xue-Mei1 ; Ma, Yun-Bao 1; Jiang, Zhi-Yong 1; Luo, Jie 1; Zhou, Jun1 ; Wang, Hong-Ling 1,2; Chen, Ji-Jun1
	2010-05-05
发表期刊	TETRAHEDRON LETTERS
ISSN	0040-4039
卷号	51 期号:18 页码:2483-2485
摘要	Swerilactones E (1), F (2), and G (3), three unusual lactones with a phenyl group, were isolated from the traditional Chinese herb of Sweat mileensis. Their structures were determined based on extensive spectroscopic analysis and X-ray single crystal crystallography. Our anti-HBV assay on the Hep G 2.2.15 cell line in vitro showed that compounds 1 and 2 exhibited significant inhibitory activities against the secretion of HBsAg with IC(50) of 0.22 and 0.70 mM and HBeAg with IC(50) of 0.52 and >6.78 nM, respectively. (C) 2010 Elsevier Ltd. All rights reserved.
关键词	Swertia Mileensis Swerilactones E-g Secoiridoid Aglycone Anti Hbv Activity
学科领域	Chemistry, Organic
DOI	10.1016/j.tetlet.2010.02.156
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000276972200027
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4304
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Geng, Chang-An,Zhang, Xue-Mei,Ma, Yun-Bao,et al. Swerilactones E-G, three unusual lactones from Swertia mileensis[J]. TETRAHEDRON LETTERS,2010,51(18):2483-2485.
APA	Geng, Chang-An.,Zhang, Xue-Mei.,Ma, Yun-Bao.,Jiang, Zhi-Yong.,Luo, Jie.,...&Chen, Ji-Jun.(2010).Swerilactones E-G, three unusual lactones from Swertia mileensis.TETRAHEDRON LETTERS,51(18),2483-2485.
MLA	Geng, Chang-An,et al."Swerilactones E-G, three unusual lactones from Swertia mileensis".TETRAHEDRON LETTERS 51.18(2010):2483-2485.

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