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Cytotoxic Monoterpenoid Indole Alkaloids from Tabernaemontana corymbosa as Potent Autophagy Inhibitors by the Attenuation of Lysosomal Acidification 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2020
作者:  Zhang, Yu;  Ding, Xiao;  Yuan, Yu-Xi;  Guo, Ling-Li;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1923Kb)  |  收藏  |  浏览/下载：133/35  |  提交时间：2021/01/05
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 11
作者:  Liu, Tangjingjun;  Xia, Lei;  Yao, Yao;  Yan, Chen;  Fan, Yanhua;  Gajendran, Babu;  Yang, Jue;  Li, You-Jun;  Chen, Juan;  Filmus, Jorge;  Spaner, David E.;  Zacksenhaus, Eldad;  Hao, Xiaojiang;  Ben-David, Yaacov
浏览  |  Adobe PDF(2055Kb)  |  收藏  |  浏览/下载：281/39  |  提交时间：2019/04/15
Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/beta-catenin transcriptional activity 期刊论文
CELL DISCOVERY, 2017, 卷号: 3, 页码: 17003
作者:  He, Xiaoli;  Zhang, Wenjuan;  Yan, Chen;  Nie, Fen;  Li, Chen;  Liu, Xiaofen;  Fei, Cong;  Li, Shengdi;  Song, Xiaomin;  Jia, Yingying;  Zeng, Rong;  Wu, Dianqing;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(3775Kb)  |  收藏  |  浏览/下载：153/38  |  提交时间：2017/12/18
Carf  Chemical Biology  Nc043  Small Molecule  Wnt Signaling  
A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30 期刊论文
CELL RESEARCH, 2014, 卷号: 24, 期号: 4, 页码: 482-496
作者:  Yue, Wen;  Chen, Ziheng;  Liu, Haiyang;  Yan, Chen;  Chen, Ming;  Feng, Du;  Yan, Chaojun;  Wu, Hao;  Du, Lei;  Wang, Yueying;  Liu, Jinhua;  Huang, Xiaohu;  Xia, Laixin;  Liu, Lei;  Wang, Xiaohui;  Jin, Haijing;  Wang, Jun;  Song, Zhiyin;  Hao, Xiaojiang;  Chen, Quan
浏览  |  Adobe PDF(1659Kb)  |  收藏  |  浏览/下载：621/58  |  提交时间：2014/05/16
Mitochondrial Fusion  Mitofusin1/2  Deubiquitinase Usp30  15-oxospiramilactone  
A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2013, 卷号: 63, 期号: SI, 页码: 485-494
作者:  Liu, Jinhua;  Mu, Chenglong;  Yue, Wen;  Li, Jie;  Ma, Biao;  Zhao, Lixia;  Liu, Lei;  Chen, Quan;  Yan, Chen;  Liu, Haiyang;  Hao, Xiaojiang;  Zhu, Yushan
浏览  |  Adobe PDF(2679Kb)  |  收藏  |  浏览/下载：315/61  |  提交时间：2013/10/16
Thioredoxin Reductase  Bim  Ros  Apoptosis  Cancer  
A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/beta-catenin signaling and colon cancer cell tumorigenesis 期刊论文
CELL RESEARCH, 2011, 卷号: 21, 期号: 5, 页码: 730-740
作者:  Wang, Wei;  Liu, Haiyang;  Wang, Sheng;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(1539Kb)  |  收藏  |  浏览/下载：287/37  |  提交时间：2012/07/25
Wnt  Small Molecule  Inhibitor  Tumorigenesis  
Screening and docking studies of natural phenolic inhibitors of carbonic anhydrase II 期刊论文
SCIENCE IN CHINA SERIES B-CHEMISTRY, 2009, 卷号: 52, 期号: 3, 页码: 332-337
作者:  HuoQiang, Huang;  Pan XuLin;  Ji ChangJiu;  Zeng GuangZhi;  Jiang LiHua;  Fu Xiang;  Liu JiKai;  Hao XiaoJiang;  Zhang YingJun;  Tan NingHua
Adobe PDF(642Kb)  |  收藏  |  浏览/下载：572/214  |  提交时间：2011/12/19
Carbonic Anhydrase Ii  Natural Inhibitors  Screening  Docking  
High-throughput screening of novel antagonists on melanin-concentrating hormone receptor-1 期刊论文
ACTA PHARMACOLOGICA SINICA, 2008, 卷号: 29, 期号: 6, 页码: 752-758
作者:  Yan, Jian-hua;  Li, Qun-yi;  Boutin, Jean A.;  Renard, M. Pierre;  Ding, Yi-xiang;  Hao, Xiao-jiang;  Zhao, Wei-min;  Wang, Ming-wei
Adobe PDF(435Kb)  |  收藏  |  浏览/下载：368/109  |  提交时间：2011/12/19
Melanin-concentrating Hormone  Melanin-concentrating Hormone Receptor-1  Antagonist