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Artemicapillasins A-N, cytotoxic coumaric acid analogues against hepatic stellate cell LX2 from Artemisia capillaris (Yin-Chen) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 117, 页码: 105441
作者:  Gao,Zhen;  Huang,Xiao-Yan;  Geng,Chang-An;  Li,Tian-Ze;  Chen,Ji-Jun
浏览  |  Adobe PDF(1872Kb)  |  收藏  |  浏览/下载：111/31  |  提交时间：2022/04/02
Artemisia capillaris  Coumaric acid analogues  Antihepatic fibrosis effects  HSC-LX2  Extracellular matrix  TRADITIONAL CHINESE HERB  ACTIVE CONSTITUENTS  LIVER FIBROSIS  
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
作者:  Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
Adobe PDF(2010Kb)  |  收藏  |  浏览/下载：104/14  |  提交时间：2022/04/02
Tripterygium wilfordii  liver injury  farnesoid X receptor  bile acid metabolism  metabolomics  
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
Adobe PDF(3665Kb)  |  收藏  |  浏览/下载：68/9  |  提交时间：2022/04/02
Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN