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Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
浏览  |  Adobe PDF(1696Kb)  |  收藏  |  浏览/下载：342/78  |  提交时间：2015/06/29
2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
(+/-)-Aspongamide A, an N-Acetyldopamine Trimer Isolated from the Insect Aspongopus chinensis, Is an Inhibitor of p-Smad3 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 2, 页码: 532-535
作者:  Yan, Yong-Ming;  Ai, Jun;  Shi, Yan-Ni;  Zuo, Zhi-Li;  Hou, Bo;  Luo, Jie;  Cheng, Yong-Xian
Adobe PDF(229Kb)  |  收藏  |  浏览/下载：448/76  |  提交时间：2014/04/09
Disease  Products  
Lingzhiols, Unprecedented Rotary Door-Shaped Meroterpenoids as Potent and Selective Inhibitors of p-Smad3 from Ganoderma lucidum 期刊论文
ORGANIC LETTERS, 2013, 卷号: 15, 期号: 21, 页码: 5488-5491
作者:  Yan, Yong-Ming;  Ai, Jun;  Zhou, Li-Li;  Chung, Arthur C. K.;  Li, Rong;  Nie, Jing;  Fang, Ping;  Wang, Xin-Long;  Luo, Jie;  Hu, Qun;  Hou, Fan-Fan;  Cheng, Yong-Xian
Adobe PDF(299Kb)  |  收藏  |  浏览/下载：645/134  |  提交时间：2014/01/13
Diabetic-nephropathy  High-glucose  Mesangial Cells  Up-regulation  Expression  Activation  Pathways  
Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-kappa B Activation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 11, 页码: 4749-4757
作者:  Zhao, Yu;  Su, Jia;  Goto, Masuo;  Morris-Natschke, Susan L.;  Li, Yan;  Zhao, Qin-Shi;  Yao, Zhu-Jun;  Lee, Kuo-Hsiung
Adobe PDF(531Kb)  |  收藏  |  浏览/下载：317/67  |  提交时间：2013/10/16
Natural-products  Biological-activity  Cancer-therapy  Paclitaxel  Taxol  Resistance  Drugs  Chemotherapy  Parthenolide  Brevifoliol  
Elucidating the Biosynthetic Pathway for Vibralactone: A Pancreatic Lipase Inhibitor with a Fused Bicyclic beta-Lactone 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 卷号: 52, 期号: 8, 页码: 2298-2302
作者:  Zhao, Pei-Ji;  Yang, Yan-Long;  Du, Liangchen;  Liu, Ji-Kai;  Zeng, Ying
Adobe PDF(842Kb)  |  收藏  |  浏览/下载：446/90  |  提交时间：2013/07/24
Biosynthesis  Isotopic Labeling  Lactones  Mass Spectrometry  Natural Products  
Isolation and Identification of Compounds Responsible for Antioxidant Capacity of Euryale ferox Seeds 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2011, 卷号: 59, 期号: 4, 页码: 1199-1204
作者:  Song, Chang-Wei;  Wang, Shu-Mei;  Zhou, Li-Li;  Hou, Fan-Fan;  Wang, Kai-Jin;  Han, Quan-Bin;  Li, Ning;  Cheng, Yong-Xian
Adobe PDF(885Kb)  |  收藏  |  浏览/下载：619/207  |  提交时间：2012/04/10
Euryale Ferox  Nymphaeaceae  Lignans  Antioxidant Activity  
Glandular Trichomes of Leucosceptrum canum Harbor Defensive Sesterterpenoids 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 卷号: 49, 期号: 26, 页码: 4471-4475
作者:  Luo, Shi-Hong;  Luo, Qian;  Niu, Xue-Mei;  Xie, Ming-Jin;  Zhao, Xu;  Schneider, Bernd;  Gershenzon, Jonathan;  Li, Sheng-Hong
Adobe PDF(550Kb)  |  收藏  |  浏览/下载：479/156  |  提交时间：2012/03/21
Antifeedant Agents  Antifungal Agents  Natural Products  Sesterterpenoids  Structure Elucidation