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Bioassay-guided isolation of saikosaponins with agonistic activity on 5-hydroxytryptamine 2C receptor from Bupleurum chinense and their potential use for the treatment of obesity 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 6, 页码: 467-473
作者:  Sun Chang-Li;  Geng Chang-An;  Huang Xiao-Yan;  Ma Yun-Bao;  Zheng Xiao-Hong;  Yang Tong-Hua;  Chen Xing-Long;  Yin Xiu-Juan;  Zhang Xue-Mei;  Chen Ji-Jun
浏览  |  Adobe PDF(746Kb)  |  收藏  |  浏览/下载：272/96  |  提交时间：2017/10/23
Bupleurum Chinense  5-hydroxytryptamine 2c (5-ht2c) Receptor  Anti-obesity  Saikosaponins  
(+/-)-Uncarilins A and B, Dimeric Isoechinulin-Type Alkaloids from Uncaria rhynchophylla 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 4, 页码: 959-964
作者:  Geng, Chang-An;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Hou, Bo;  Li, Tian-Ze;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1424Kb)  |  收藏  |  浏览/下载：363/92  |  提交时间：2017/08/29
In vitro assessment of the glucose-lowering effects of berberrubine-9-O-beta-D-glucuronide, an active metabolite of berberrubine 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 3, 页码: 351-361
作者:  Yang, Na;  Sun, Run-Bin;  Chen, Xing-Long;  Zhen, Le;  Ge, Chun;  Zhao, Yu-Qing;  He, Jun;  Geng, Jian-Liang;  Guo, Jia-Hua;  Yu, Xiao-Yi;  Fei, Fei;  Feng, Si-Qi;  Zhu, Xuan-Xuan;  Wang, Hong-Bo;  Fu, Feng-Hua;  Aa, Ji-Ye;  Wang, Guang-Ji
浏览  |  Adobe PDF(4661Kb)  |  收藏  |  浏览/下载：271/90  |  提交时间：2017/05/19
Hyperglycemia  Glucose-lowering Effect  Berberine  Berberrubine  Glucuronide  Alpha-glycosidase  Hfd-induced Hyperglycemia Model Of C57bl/6 Mice  Human Normal Liver Cell Line L-o2  Pharmacokinetics  
Global identification strategy based on mass spectrometry for studying protostane triterpenoids in rhizomes of Alisma orientalis 期刊论文
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2017, 卷号: 414, 页码: 70-79
作者:  Chen, Xinglong;  Geng, Changan;  Zhang, Xiuqiong;  Li, Tianze;  Chen, Jijun
浏览  |  Adobe PDF(1578Kb)  |  收藏  |  浏览/下载：337/63  |  提交时间：2017/05/19
Lcms-it-tof  Global Identification Strategy  Diagnostic Ions  Protostane Triterpenoids  Alisma Orientalis  
Chemical and biological comparison of different sections of Uncaria rhynchophylla (Gou-Teng) 期刊论文
EUROPEAN JOURNAL OF MASS SPECTROMETRY, 2017, 卷号: 23, 期号: 1, 页码: 11-21
作者:  Zhang, Jian-Gang;  Geng, Chang-An;  Huang, Xiao-Yan;  Chen, Xing-Long;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(521Kb)  |  收藏  |  浏览/下载：372/72  |  提交时间：2017/06/30
Uncaria Rhynchophylla  Gou Teng  Lc-ms Analysis  Chemical Profiles  Mt1/2 And 5-ht1a/2c Receptors  Indole Alkaloids  
Catalytic Asymmetric Total Synthesis of (+)- and (-)-Paeoveitol via a Hetero-Diels-Alder Reaction 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 3, 页码: 429-431
作者:  Li,Tian-Ze;  Geng,Chang-An;  Yin,Xiu-Juan;  Yang,Tong-Hua;  Chen,Xing-Long;  Huang,Xiao-Yan;  Ma,Yun-Bao;  Zhang,Xue-Mei;  Chen,Ji-Jun
浏览  |  Adobe PDF(553Kb)  |  收藏  |  浏览/下载：183/56  |  提交时间：2017/10/23
Ortho-quinone Methides  Paeonia-veitchii  Natural-products  Paeoveitol  
Bioactivity-guided synthesis of gramine derivatives as new MT1 and 5-HT1A receptors agonists 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2017, 卷号: 19, 期号: 6, 页码: 610-622
作者:  Yin, Xiu-Juan;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Geng, Chang-An;  Li, Tian-Ze;  Chen, Xing-Long;  Yang, Tong-Hua;  Zhou, Jun;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(2718Kb)  |  收藏  |  浏览/下载：348/62  |  提交时间：2017/07/10
Gramine  Melatonin Receptor  5-hydroxy-tryptamine Receptor  Agonistic Activity  Structure-activity Relationships