Global identification strategy based on mass spectrometry for studying protostane triterpenoids in rhizomes of Alisma orientalis
Chen, Xinglong1,2; Geng, Changan1,3; Zhang, Xiuqiong1,2; Li, Tianze1,3; Chen, Jijun1,3
2017-03-01
Source PublicationINTERNATIONAL JOURNAL OF MASS SPECTROMETRY
Volume414Pages:70-79
AbstractThe liquid chromatography hybrid ion trap time-of-flight mass spectrometry (LCMS-IT-TOF) combined with a global identification strategy was applied to studying the protostane triterpenoids (PTs) in the rhizomes of Alisma orientalis in this paper. Initially, the MSn analyses of four reference compounds were performed to summarize the fragmentation rules of PTs. Subsequently, a series of ions of PTs were presented by LC-MSn analyses of the crude extract of alismatis rhizome, from which six ions at m/z 339, 353,365, 381,383 and 397 with high frequency of occurrence were selected as diagnostic ions to classify the peaks. Twenty peaks were classified into six families based on common ions. A network was established for the six families via diagnostic ions. 20 PTs including 1 new compound and 19 known ones were characterized through such strategy, fragmentation rules and references. Ultimately, the detected new compound and two known compounds were isolated from the total extract of A. orientalis under the guide of above method, of which the new compound was identified as 11-deoxylalisol F by MS and NMR spectrum. This systematical investigation on the PTs demonstrated that such a strategy could be widely used in the analysis and separation of natural products. (C) 2017 Elsevier B.V. All rights reserved.
KeywordLcms-it-tof Global Identification Strategy Diagnostic Ions Protostane Triterpenoids Alisma Orientalis
DOI10.1016/j.ijms.2017.01.004
Indexed BySCI
Language英语
WOS Research AreaPhysics ; Spectroscopy
WOS SubjectPhysics, Atomic, Molecular & Chemical ; Spectroscopy
WOS IDWOS:000397692200010
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/51004
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Yunnan Key Lab Nat Med Chem, Kunming 650201, Peoples R China
Recommended Citation
GB/T 7714
Chen, Xinglong,Geng, Changan,Zhang, Xiuqiong,et al. Global identification strategy based on mass spectrometry for studying protostane triterpenoids in rhizomes of Alisma orientalis[J]. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY,2017,414:70-79.
APA Chen, Xinglong,Geng, Changan,Zhang, Xiuqiong,Li, Tianze,&Chen, Jijun.(2017).Global identification strategy based on mass spectrometry for studying protostane triterpenoids in rhizomes of Alisma orientalis.INTERNATIONAL JOURNAL OF MASS SPECTROMETRY,414,70-79.
MLA Chen, Xinglong,et al."Global identification strategy based on mass spectrometry for studying protostane triterpenoids in rhizomes of Alisma orientalis".INTERNATIONAL JOURNAL OF MASS SPECTROMETRY 414(2017):70-79.
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