Tabernabovines A-C: Three Monoterpenoid Indole Alkaloids from the Leaves of Tabernaemontana bovina

doi:10.1021/acs.orglett.9b02060

	Tabernabovines A-C: Three Monoterpenoid Indole Alkaloids from the Leaves of Tabernaemontana bovina
	Yu, Yang 1,2; Bao, Mei-Fen 1,2; Wu, Jing 1,2; Chen, Jing 1,2; Yang, Yu-Rong1,3 ; Schinnerl, Johann 4; Cai, Xiang-Hai1,3
通讯作者	Cai, Xiang-Hai(xhcai@mail.kib.ac.cn)
	2019-08-02
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	21 期号:15 页码:5938-5942
摘要	Three monoterpenoid indole alkaloids (MIAs), tabernabovines A-C (1-3), were isolated from Tabernaemontana bovina. They were elucidated by spectroscopic data and computational calculations. Unlike precursors of MIAs, strictosidine and alstrostine A, alkaloid 1 consists of tryptamine and secologanin in a 2:1 ratio. Alkaloid 2 is a cage compound, and 3 possesses a bridged ring. Tabernabovine A exhibited inhibitory activity against NO production with IC50 44.1 mu M compared to L-NMMA with IC50 of 48.6 mu M.
DOI	10.1021/acs.orglett.9b02060
收录类别	SCI
语种	英语
WOS记录号	WOS:000480371600035
引用统计	被引频次：11[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/68340
专题	植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Cai, Xiang-Hai
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China 4.Univ Vienna, Div Systemat & Evolutionary Bot, Chemodivers Res Grp, Rennweg 14, A-1030 Vienna, Austria
推荐引用方式 GB/T 7714	Yu, Yang,Bao, Mei-Fen,Wu, Jing,et al. Tabernabovines A-C: Three Monoterpenoid Indole Alkaloids from the Leaves of Tabernaemontana bovina[J]. ORGANIC LETTERS,2019,21(15):5938-5942.
APA	Yu, Yang.,Bao, Mei-Fen.,Wu, Jing.,Chen, Jing.,Yang, Yu-Rong.,...&Cai, Xiang-Hai.(2019).Tabernabovines A-C: Three Monoterpenoid Indole Alkaloids from the Leaves of Tabernaemontana bovina.ORGANIC LETTERS,21(15),5938-5942.
MLA	Yu, Yang,et al."Tabernabovines A-C: Three Monoterpenoid Indole Alkaloids from the Leaves of Tabernaemontana bovina".ORGANIC LETTERS 21.15(2019):5938-5942.

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