| Highly oxygenated meroterpenoids from the Antarctic fungus Aspergillus terreus | |
Feng, Wenya1; Chen, Chunmei1; Mo, Shuyuan1; Qi, Changxing1; Gong, Jiaojiao1; Li, Xiao-Nian2; Zhou, Qun1; Zhou, Yuan1 ; Li, Dongyan3; Lai, Yongji4; Zhu, Hucheng1; Wang, Jianping1; Zhang, Yonghui1
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| 通讯作者 | Zhu, Hucheng(zhuhucheng@hust.edu.cn) ; Wang, Jianping(jpwang1001@163.com) ; Zhang, Yonghui(zhangyh@mails.tjmu.edu.cn) |
| 2019-08-01 | |
| 发表期刊 | PHYTOCHEMISTRY
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| ISSN | 0031-9422 |
| 卷号 | 164页码:184-191 |
| 摘要 | Eleven highly oxygenated meroterpenoids, named terreustoxins A - K, along with five known analogues, were isolated from the Antarctic fungus Aspergillus terreus. The structures and absolute configurations of these un-described compounds were characterized by NMR spectroscopy, single-crystal X-ray crystallography, and ECD experiments. Terreustoxins A - D are the first examples of meroterpenoids with two ortho-hydroxy groups at C-6 and C-7 in the terretonins family. Terreustoxin C and terretonin inhibited the proliferation of Con A-induced murine T cells at the concentration of 10 mu M. |
| 关键词 | Aspergillus terreus (Trichocomaceae) Antarctic fungus Terreustoxins Immunosuppressive activity |
| DOI | 10.1016/j.phytochem.2019.05.015 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000475996800021 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/68260 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Zhu, Hucheng; Wang, Jianping; Zhang, Yonghui |
| 作者单位 | 1.Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Pharm, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Hubei, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 3.Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Pharm, Wuhan 430030, Hubei, Peoples R China 4.Huazhong Univ Sci & Technol, Cent Hosp Wuhan, Dept Pharm, Tongji Med Coll, Wuhan 430030, Hubei, Peoples R China |
| 推荐引用方式 GB/T 7714 | Feng, Wenya,Chen, Chunmei,Mo, Shuyuan,et al. Highly oxygenated meroterpenoids from the Antarctic fungus Aspergillus terreus[J]. PHYTOCHEMISTRY,2019,164:184-191. |
| APA | Feng, Wenya.,Chen, Chunmei.,Mo, Shuyuan.,Qi, Changxing.,Gong, Jiaojiao.,...&Zhang, Yonghui.(2019).Highly oxygenated meroterpenoids from the Antarctic fungus Aspergillus terreus.PHYTOCHEMISTRY,164,184-191. |
| MLA | Feng, Wenya,et al."Highly oxygenated meroterpenoids from the Antarctic fungus Aspergillus terreus".PHYTOCHEMISTRY 164(2019):184-191. |
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| Feng-2019-Highly oxy（635KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
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