Highly oxygenated meroterpenoids from the Antarctic fungus Aspergillus terreus

doi:10.1016/j.phytochem.2019.05.015

	Highly oxygenated meroterpenoids from the Antarctic fungus Aspergillus terreus
	Feng, Wenya 1; Chen, Chunmei 1; Mo, Shuyuan 1; Qi, Changxing 1; Gong, Jiaojiao 1; Li, Xiao-Nian 2; Zhou, Qun 1; Zhou, Yuan1 ; Li, Dongyan 3; Lai, Yongji 4; Zhu, Hucheng 1; Wang, Jianping 1; Zhang, Yonghui 1
通讯作者	Zhu, Hucheng(zhuhucheng@hust.edu.cn) ; Wang, Jianping(jpwang1001@163.com) ; Zhang, Yonghui(zhangyh@mails.tjmu.edu.cn)
	2019-08-01
发表期刊	PHYTOCHEMISTRY
ISSN	0031-9422
卷号	164 页码:184-191
摘要	Eleven highly oxygenated meroterpenoids, named terreustoxins A - K, along with five known analogues, were isolated from the Antarctic fungus Aspergillus terreus. The structures and absolute configurations of these un-described compounds were characterized by NMR spectroscopy, single-crystal X-ray crystallography, and ECD experiments. Terreustoxins A - D are the first examples of meroterpenoids with two ortho-hydroxy groups at C-6 and C-7 in the terretonins family. Terreustoxin C and terretonin inhibited the proliferation of Con A-induced murine T cells at the concentration of 10 mu M.
关键词	Aspergillus terreus (Trichocomaceae) Antarctic fungus Terreustoxins Immunosuppressive activity
DOI	10.1016/j.phytochem.2019.05.015
收录类别	SCI
语种	英语
WOS记录号	WOS:000475996800021
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/68260
专题	植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Zhu, Hucheng; Wang, Jianping; Zhang, Yonghui
作者单位	1.Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Pharm, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Hubei, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 3.Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Pharm, Wuhan 430030, Hubei, Peoples R China 4.Huazhong Univ Sci & Technol, Cent Hosp Wuhan, Dept Pharm, Tongji Med Coll, Wuhan 430030, Hubei, Peoples R China
推荐引用方式 GB/T 7714	Feng, Wenya,Chen, Chunmei,Mo, Shuyuan,et al. Highly oxygenated meroterpenoids from the Antarctic fungus Aspergillus terreus[J]. PHYTOCHEMISTRY,2019,164:184-191.
APA	Feng, Wenya.,Chen, Chunmei.,Mo, Shuyuan.,Qi, Changxing.,Gong, Jiaojiao.,...&Zhang, Yonghui.(2019).Highly oxygenated meroterpenoids from the Antarctic fungus Aspergillus terreus.PHYTOCHEMISTRY,164,184-191.
MLA	Feng, Wenya,et al."Highly oxygenated meroterpenoids from the Antarctic fungus Aspergillus terreus".PHYTOCHEMISTRY 164(2019):184-191.

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