Synergistic use of NMR computation and quantitative interproton distance analysis in the structural determination of neokadcoccitane A, a rearranged triterpenoid featuring an aromatic ring D from Kadsura coccinea | |
Xu, Hou-Chao1,2,3; Hu, Kun1,2; Shi, Xiao-Huo1,2; Tang, Jian-Wei1,2; Li, Xiao-Nian1,2; Sun, Han-Dong1,2; Puno, Pema-Tenzin1,2 | |
通讯作者 | Puno, Pema-Tenzin(punopematenzin@mail.kib.ac.cn) |
2019-05-21 | |
发表期刊 | ORGANIC CHEMISTRY FRONTIERS |
ISSN | 2052-4129 |
卷号 | 6期号:10页码:1619-1626 |
摘要 | Neokadcoccitane A (1), an unprecedented 14(13. 12): 28(14. 8)-diabeo-3,4-secolanostane triterpenoid possessing an aromatic ring D and an unusual Me-21 orientation, along with two novel 14(13. 12)-abeo-3,4- seco-norlanostane triterpenoids featuring three-and one-carbon degradation, respectively (2 and 3), were isolated from the roots of Kadsura coccinea. The absolute configuration of 1 was determined by the synergistic use of NMR computation, quantitative interproton distance analysis, and TDDFT ECD calculation, while that of 2 was established using X-ray diffraction. 1 was found to exhibit moderate anti-platelet aggregation activity. |
DOI | 10.1039/c9qo00281b |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000468001500011 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/67498 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
通讯作者 | Puno, Pema-Tenzin |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Xu, Hou-Chao,Hu, Kun,Shi, Xiao-Huo,et al. Synergistic use of NMR computation and quantitative interproton distance analysis in the structural determination of neokadcoccitane A, a rearranged triterpenoid featuring an aromatic ring D from Kadsura coccinea[J]. ORGANIC CHEMISTRY FRONTIERS,2019,6(10):1619-1626. |
APA | Xu, Hou-Chao.,Hu, Kun.,Shi, Xiao-Huo.,Tang, Jian-Wei.,Li, Xiao-Nian.,...&Puno, Pema-Tenzin.(2019).Synergistic use of NMR computation and quantitative interproton distance analysis in the structural determination of neokadcoccitane A, a rearranged triterpenoid featuring an aromatic ring D from Kadsura coccinea.ORGANIC CHEMISTRY FRONTIERS,6(10),1619-1626. |
MLA | Xu, Hou-Chao,et al."Synergistic use of NMR computation and quantitative interproton distance analysis in the structural determination of neokadcoccitane A, a rearranged triterpenoid featuring an aromatic ring D from Kadsura coccinea".ORGANIC CHEMISTRY FRONTIERS 6.10(2019):1619-1626. |
条目包含的文件 | 下载所有文件 | |||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
xu2019.pdf(762KB) | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论