A practical total synthesis of (+/-)-cermizine D and a formal synthesis of (+/-)-cermizine C

doi:10.3184/174751918X15271572210923

	A practical total synthesis of (+/-)-cermizine D and a formal synthesis of (+/-)-cermizine C
	Shi, Xin 1,2,3; Bao, Ying 1,2,3; Deng, Zhen-Tao 1,2,3; Zhu, Yu 2,3; Shao, Li-Dong 2; Zhang, Hong-Bin 1; Zhao, Qin-Shi2
	2018-06-01
发表期刊	JOURNAL OF CHEMICAL RESEARCH
ISSN	1747-5198
期号	5 页码:274-279
摘要	A practical total synthesis of (+/-)-cermizine D and a formal synthesis of (+/-)-cermizine C were achieved. The four-step total synthesis comprised mainly a Michael addition, a Weinreb amide-activated substitution and a sequence of ketalation/PtO2-catalysed dearomatisation/reductive amination reactions that resulted in ring closure in 13.7% overall yield. The formal synthesis was accomplished in 29.7% overall yield.
关键词	Cermizine c Cermizine d Total Synthesis Michael Addition Reductive Amination
DOI	10.3184/174751918X15271572210923
语种	英语
WOS记录号	WOS:000435470600012
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/61421
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Yunnan Univ, Sch Chem Sci & Technol, Minist Educ, Key Lab Med Chem Nat Resources, Kunming 650091, Yunnan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Shi, Xin,Bao, Ying,Deng, Zhen-Tao,et al. A practical total synthesis of (+/-)-cermizine D and a formal synthesis of (+/-)-cermizine C[J]. JOURNAL OF CHEMICAL RESEARCH,2018(5):274-279.
APA	Shi, Xin.,Bao, Ying.,Deng, Zhen-Tao.,Zhu, Yu.,Shao, Li-Dong.,...&Zhao, Qin-Shi.(2018).A practical total synthesis of (+/-)-cermizine D and a formal synthesis of (+/-)-cermizine C.JOURNAL OF CHEMICAL RESEARCH(5),274-279.
MLA	Shi, Xin,et al."A practical total synthesis of (+/-)-cermizine D and a formal synthesis of (+/-)-cermizine C".JOURNAL OF CHEMICAL RESEARCH .5(2018):274-279.