A practical total synthesis of (+/-)-cermizine D and a formal synthesis of (+/-)-cermizine C
Shi, Xin1,2,3; Bao, Ying1,2,3; Deng, Zhen-Tao1,2,3; Zhu, Yu2,3; Shao, Li-Dong2; Zhang, Hong-Bin1; Zhao, Qin-Shi2
2018-06-01
Source PublicationJOURNAL OF CHEMICAL RESEARCH
ISSN1747-5198
Issue5Pages:274-279
AbstractA practical total synthesis of (+/-)-cermizine D and a formal synthesis of (+/-)-cermizine C were achieved. The four-step total synthesis comprised mainly a Michael addition, a Weinreb amide-activated substitution and a sequence of ketalation/PtO2-catalysed dearomatisation/reductive amination reactions that resulted in ring closure in 13.7% overall yield. The formal synthesis was accomplished in 29.7% overall yield.
KeywordCermizine c Cermizine d Total Synthesis Michael Addition Reductive Amination
DOI10.3184/174751918X15271572210923
Language英语
WOS IDWOS:000435470600012
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/61421
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Yunnan Univ, Sch Chem Sci & Technol, Minist Educ, Key Lab Med Chem Nat Resources, Kunming 650091, Yunnan, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Shi, Xin,Bao, Ying,Deng, Zhen-Tao,et al. A practical total synthesis of (+/-)-cermizine D and a formal synthesis of (+/-)-cermizine C[J]. JOURNAL OF CHEMICAL RESEARCH,2018(5):274-279.
APA Shi, Xin.,Bao, Ying.,Deng, Zhen-Tao.,Zhu, Yu.,Shao, Li-Dong.,...&Zhao, Qin-Shi.(2018).A practical total synthesis of (+/-)-cermizine D and a formal synthesis of (+/-)-cermizine C.JOURNAL OF CHEMICAL RESEARCH(5),274-279.
MLA Shi, Xin,et al."A practical total synthesis of (+/-)-cermizine D and a formal synthesis of (+/-)-cermizine C".JOURNAL OF CHEMICAL RESEARCH .5(2018):274-279.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Shi, Xin]'s Articles
[Bao, Ying]'s Articles
[Deng, Zhen-Tao]'s Articles
Baidu academic
Similar articles in Baidu academic
[Shi, Xin]'s Articles
[Bao, Ying]'s Articles
[Deng, Zhen-Tao]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Shi, Xin]'s Articles
[Bao, Ying]'s Articles
[Deng, Zhen-Tao]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.