Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus
Wan, Luo-Sheng1,5; Nian, Yin2,3; Peng, Xing-Rong1; Shao, Li-Dong1; Li, Xiao-Nian1; Yang, Jian2,3; Zhou, Ming2,3,4; Qiu, Ming-Hua1
2018-05-18
发表期刊ORGANIC LETTERS
ISSN1523-7060
卷号20期号:10页码:3074-3078
摘要Pepluanols C and D (1 and 2), featuring unprecedented 5/5/10 with out,out-[7.2.1]bicylcododecane core and 6/6/7/3 fused-ring skeletons, respectively, were isolated from Euphorbia peplus. Their chemical structures and absolute configurations were determined by a series of extensive spectroscopic methods, and X-ray diffraction analysis. In addition, pepluanols C and D showed 31.6 +/- 8.3% and 30.5 +/- 2.8% peak current inhibition on the K(v)1.3 potassium channel at 30 mu M.
DOI10.1021/acs.orglett.8b01114
语种英语
WOS记录号WOS:000432900200064
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被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/61415
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Chinese Acad Sci, Kunming Inst Zool, Key Lab Anim Models & Human Diease Mech, Kunming 650223, Yunnan, Peoples R China
3.Chinese Acad Sci, Ion Channel Res & Drug Dev Ctr, Kunming Inst Zool, Kunming 650223, Yunnan, Peoples R China
4.Baylor Coll Med, Verna & Marrs McLean Dept Biochem & Mol Biol, Houston, TX 77030 USA
5.Huazhong Univ Sci & Technol, Pharm Dept, Hubei Key Lab Nat Med Chem & Resource Evaluat, Tongji Med Sch, Wuhan 430030, Hubei, Peoples R China
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Wan, Luo-Sheng,Nian, Yin,Peng, Xing-Rong,et al. Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus[J]. ORGANIC LETTERS,2018,20(10):3074-3078.
APA Wan, Luo-Sheng.,Nian, Yin.,Peng, Xing-Rong.,Shao, Li-Dong.,Li, Xiao-Nian.,...&Qiu, Ming-Hua.(2018).Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus.ORGANIC LETTERS,20(10),3074-3078.
MLA Wan, Luo-Sheng,et al."Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus".ORGANIC LETTERS 20.10(2018):3074-3078.
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