Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus

doi:10.1021/acs.orglett.8b01114

	Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus
	Wan, Luo-Sheng 1,5; Nian, Yin2,3 ; Peng, Xing-Rong 1; Shao, Li-Dong 1; Li, Xiao-Nian 1; Yang, Jian 2,3; Zhou, Ming 2,3,4; Qiu, Ming-Hua1
	2018-05-18
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	20 期号:10 页码:3074-3078
摘要	Pepluanols C and D (1 and 2), featuring unprecedented 5/5/10 with out,out-[7.2.1]bicylcododecane core and 6/6/7/3 fused-ring skeletons, respectively, were isolated from Euphorbia peplus. Their chemical structures and absolute configurations were determined by a series of extensive spectroscopic methods, and X-ray diffraction analysis. In addition, pepluanols C and D showed 31.6 +/- 8.3% and 30.5 +/- 2.8% peak current inhibition on the K(v)1.3 potassium channel at 30 mu M.
DOI	10.1021/acs.orglett.8b01114
语种	英语
WOS记录号	WOS:000432900200064
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/61415
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Zool, Key Lab Anim Models & Human Diease Mech, Kunming 650223, Yunnan, Peoples R China 3.Chinese Acad Sci, Ion Channel Res & Drug Dev Ctr, Kunming Inst Zool, Kunming 650223, Yunnan, Peoples R China 4.Baylor Coll Med, Verna & Marrs McLean Dept Biochem & Mol Biol, Houston, TX 77030 USA 5.Huazhong Univ Sci & Technol, Pharm Dept, Hubei Key Lab Nat Med Chem & Resource Evaluat, Tongji Med Sch, Wuhan 430030, Hubei, Peoples R China
推荐引用方式 GB/T 7714	Wan, Luo-Sheng,Nian, Yin,Peng, Xing-Rong,et al. Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus[J]. ORGANIC LETTERS,2018,20(10):3074-3078.
APA	Wan, Luo-Sheng.,Nian, Yin.,Peng, Xing-Rong.,Shao, Li-Dong.,Li, Xiao-Nian.,...&Qiu, Ming-Hua.(2018).Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus.ORGANIC LETTERS,20(10),3074-3078.
MLA	Wan, Luo-Sheng,et al."Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus".ORGANIC LETTERS 20.10(2018):3074-3078.