| Nicotabin A, a Sesquiterpenoid Derivative from Nicotiana tabacum | |
Feng, Tao1; Li, Xue-Mei2; He, Jun1 ; Ai, Hong-Lian1; Chen, He-Ping1; Li, Xiao-Nian3; Li, Zheng-Hui1; Liu, Ji-Kai1
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| 2017-10-06 | |
| 发表期刊 | ORGANIC LETTERS
 |
| ISSN | 1523-7060 |
| 卷号 | 19期号:19页码:5201-5203 |
| 摘要 | Nicotabin A (1), a sesquiterpenoid derivative possessing a fused 5/6/5/5/5 ring system, was isolated from leaves of Nicotiana tabacum. The structure was elucidated by extensive spectroscopic methods and confirmed by single crystal X-ray diffraction. The plausible biosynthetic pathway for 1 was proposed. Compound 1 inhibited nitric oxide production in LPS-activated RAW264.7 macro-phages with an IC50 of 22.1 mu M. |
| DOI | 10.1021/acs.orglett.7b02559 |
| 语种 | 英语 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/60298 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China 2.Plant Protect & Quarantine Stn Dehong, Dehong 678400, Peoples R China 3.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Feng, Tao,Li, Xue-Mei,He, Jun,et al. Nicotabin A, a Sesquiterpenoid Derivative from Nicotiana tabacum[J]. ORGANIC LETTERS,2017,19(19):5201-5203. |
| APA | Feng, Tao.,Li, Xue-Mei.,He, Jun.,Ai, Hong-Lian.,Chen, He-Ping.,...&Liu, Ji-Kai.(2017).Nicotabin A, a Sesquiterpenoid Derivative from Nicotiana tabacum.ORGANIC LETTERS,19(19),5201-5203. |
| MLA | Feng, Tao,et al."Nicotabin A, a Sesquiterpenoid Derivative from Nicotiana tabacum".ORGANIC LETTERS 19.19(2017):5201-5203. |
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| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| feng2017.pdf（527KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
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