奇士乐对免疫性肝损伤小鼠的保护作用
姜辉 ; 吴芙蓉 ; 夏伦祝 ; 陈纪军 ; 李俊
2010
Source Publication中国中医急症
ISSN1004-745X
Issue6Pages:990-992
Abstract目的研究奇士乐对卡介苗联合脂多糖所致免疫性肝损伤小鼠的保护作用。方法采用卡介苗2.5mg静脉注射致敏小鼠,第10日给予脂多糖7.5μg静脉注射,复制小鼠免疫性肝损伤模型,连续给药10d。分光光度法测定血清中丙氨酸氨基转移酶(ALT)、天门冬酸氨基转移酶(AST)含量;HE染色法观测小鼠肝脏病理学变化;免疫组化技术观察肝组织肿瘤坏死因子(TNF—α)的表达情况。结果奇士乐能降低免疫性肝损伤小鼠脾脏、肝脏指数和血清中ALT、AST的含量;减轻肝组织病理损伤程度;抑制肝脏中TNF-α的表达。结论奇士乐对免疫性肝损伤小鼠具有保护作用。
Keyword免疫性肝损伤 肿瘤坏死因子 奇士乐
Indexed Bycscd
Language中文
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/5737
Collection植物化学与西部植物资源持续利用国家重点实验室
Recommended Citation
GB/T 7714
姜辉,吴芙蓉,夏伦祝,等. 奇士乐对免疫性肝损伤小鼠的保护作用[J]. 中国中医急症,2010(6):990-992.
APA 姜辉,吴芙蓉,夏伦祝,陈纪军,&李俊.(2010).奇士乐对免疫性肝损伤小鼠的保护作用.中国中医急症(6),990-992.
MLA 姜辉,et al."奇士乐对免疫性肝损伤小鼠的保护作用".中国中医急症 .6(2010):990-992.
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