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题名: Spirocyclic Acylphloroglucinol Derivatives from Hypericum beanii
作者: Chen, Xuan-Qin1, 2, 3; null(李艳)1; Li, Kun-Zhi2; Peng, Li-Yan1; He, Juan1; Wang, Kou1; Pan, Zheng-Hong1; Cheng, Xiao1; Li, Ming-Ming1; null(赵勤实)1; null(许刚)1
刊名: CHEMICAL & PHARMACEUTICAL BULLETIN
关键词: Hypericum beanii ; acylphloroglucinol ; hyperbeanol A ; hyperbeanol B ; hyperbeanol C ; hyperbeanol D
英文摘要: Four new acylphloroglucinols with an unusual 6/6/5 spirocyclic skeleton, hyperbeanols A-D (1-4), were isolated from the methanol extract of Hypericum beanii along with 16 known compounds. Their structures were established on the basis of spectroscopic and X-ray diffraction analysis. Hyperbeanols A-C were three stereoisomers different only at the relative configuration of C-4 and C-13, which were distinguished by the nuclear Oyerhauser effect spectroscopy (NOESY) spectroscopic data in combination with the single X-ray analysis of hyperbeanol A (1). The cytotoxic activity of hyperbeanols A D against the cancer cell lines SK-BR-3, HL-60, SMMC-7721, PANC-1, MCF-7, and K562 was also evaluated.
出版日期: 2011-10-01
卷号: 59, 期号:10, 页码:1250-1253
语种: 英语
ISSN号: 0009-2363
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/5541
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
2.Kunming Univ Sci & Technol, Biotechnol Res Ctr, Kunming 650224, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China

Recommended Citation:
Chen, XQ; Li, Y; Li, KZ; Peng, LY; He, J; Wang, K; Pan, ZH; Cheng, X; Li, MM; Zhao, QS; Xu, G.Spirocyclic Acylphloroglucinol Derivatives from Hypericum beanii,CHEMICAL & PHARMACEUTICAL BULLETIN,2011,59(10):1250-1253
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