| Spirocyclic Acylphloroglucinol Derivatives from Hypericum beanii | |
Chen, Xuan-Qin1,2,3; Li, Yan1 ; Li, Kun-Zhi2; Peng, Li-Yan1; He, Juan1; Wang, Kou1; Pan, Zheng-Hong1; Cheng, Xiao1; Li, Ming-Ming1; Zhao, Qin-Shi1; Xu, Gang1
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| 通讯作者 | Xu, G (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China |
| 2011-10-01 | |
| 发表期刊 | CHEMICAL & PHARMACEUTICAL BULLETIN
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| ISSN | 0009-2363 |
| 卷号 | 59期号:10页码:1250-1253 |
| 摘要 | Four new acylphloroglucinols with an unusual 6/6/5 spirocyclic skeleton, hyperbeanols A-D (1-4), were isolated from the methanol extract of Hypericum beanii along with 16 known compounds. Their structures were established on the basis of spectroscopic and X-ray diffraction analysis. Hyperbeanols A-C were three stereoisomers different only at the relative configuration of C-4 and C-13, which were distinguished by the nuclear Oyerhauser effect spectroscopy (NOESY) spectroscopic data in combination with the single X-ray analysis of hyperbeanol A (1). The cytotoxic activity of hyperbeanols A D against the cancer cell lines SK-BR-3, HL-60, SMMC-7721, PANC-1, MCF-7, and K562 was also evaluated. |
| 关键词 | Hypericum Beanii Acylphloroglucinol Hyperbeanol a Hyperbeanol b Hyperbeanol c Hyperbeanol d |
| 学科领域 | Pharmacology & Pharmacy ; Chemistry |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000295391200007 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/5541 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Kunming Univ Sci & Technol, Biotechnol Res Ctr, Kunming 650224, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Xuan-Qin,Li, Yan,Li, Kun-Zhi,et al. Spirocyclic Acylphloroglucinol Derivatives from Hypericum beanii[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2011,59(10):1250-1253. |
| APA | Chen, Xuan-Qin.,Li, Yan.,Li, Kun-Zhi.,Peng, Li-Yan.,He, Juan.,...&Xu, Gang.(2011).Spirocyclic Acylphloroglucinol Derivatives from Hypericum beanii.CHEMICAL & PHARMACEUTICAL BULLETIN,59(10),1250-1253. |
| MLA | Chen, Xuan-Qin,et al."Spirocyclic Acylphloroglucinol Derivatives from Hypericum beanii".CHEMICAL & PHARMACEUTICAL BULLETIN 59.10(2011):1250-1253. |
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