Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi

doi:10.1055/s-0028-1088331

	Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi
	Hu, Zhuo 1; Zhan, Rui 2,3; Du, Xue 2; Su, Jia 2; Li, Xiao-Nian 2; Yang, Jian-Hong 2; Zhang, Hai-Bo 2; Li, Yan2 ; Sun, Han-Dong2 ; Li, Gan-Peng 1; Pu, Jian-Xin2
通讯作者	Li, GP (reprint author), Yunnan Nationalities Univ, Coll Chem & Biotechnol, Kunming 650031, Peoples R China
	2011-12-01
发表期刊	CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN	0009-2363
卷号	59 期号:12 页码:1562-1566
摘要	Five new ent-kaurane diterpenoids, isodonhenrins A-E (1-5), together with thirteen known ones were isolated from the aerial parts of Isodon henryi. Their structures were identified by means of extensive spectroscopic analysis, and the absolute configurations of 1 were determined by single-crystal X-ray diffraction. Most of the diterpenoids were evaluated for their cytotoxicity against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cell lines. Compound 17 showed significant inhibitory effects on five cell lines, and compounds 6, 9, 10, 11, 12 and 16 exhibited selective activity.
关键词	Isodon Henryi Diterpenoid Isodonhenrin
学科领域	Pharmacology & Pharmacy ; Chemistry
DOI	10.1055/s-0028-1088331
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000297392300020
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/5535
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Yunnan Nationalities Univ, Coll Chem & Biotechnol, Kunming 650031, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Hu, Zhuo,Zhan, Rui,Du, Xue,et al. Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2011,59(12):1562-1566.
APA	Hu, Zhuo.,Zhan, Rui.,Du, Xue.,Su, Jia.,Li, Xiao-Nian.,...&Pu, Jian-Xin.(2011).Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi.CHEMICAL & PHARMACEUTICAL BULLETIN,59(12),1562-1566.
MLA	Hu, Zhuo,et al."Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi".CHEMICAL & PHARMACEUTICAL BULLETIN 59.12(2011):1562-1566.

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