Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi
Hu, Zhuo1; Zhan, Rui2,3; Du, Xue2; Su, Jia2; Li, Xiao-Nian2; Yang, Jian-Hong2; Zhang, Hai-Bo2; Li, Yan2; Sun, Han-Dong2; Li, Gan-Peng1; Pu, Jian-Xin2
2011-12-01
发表期刊CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN0009-2363
卷号59期号:12页码:1562-1566
摘要Five new ent-kaurane diterpenoids, isodonhenrins A-E (1-5), together with thirteen known ones were isolated from the aerial parts of Isodon henryi. Their structures were identified by means of extensive spectroscopic analysis, and the absolute configurations of 1 were determined by single-crystal X-ray diffraction. Most of the diterpenoids were evaluated for their cytotoxicity against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cell lines. Compound 17 showed significant inhibitory effects on five cell lines, and compounds 6, 9, 10, 11, 12 and 16 exhibited selective activity.
关键词Isodon Henryi Diterpenoid Isodonhenrin
资助信息NSFC-Joint Foundation of Yunnan Province[U0832602]; Major State Basic Research Development Program of China[2009CB522300, 2009CB940900]; Science and Technology Program of Yunnan Province[2008IF010, 2008CD162]; NSFC[81172939]; Major Direction Projection Foundation[2010KIBA05]
收录类别SCI ; IC
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5535
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Yunnan Nationalities Univ, Coll Chem & Biotechnol, Kunming 650031, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714
Hu, Zhuo,Zhan, Rui,Du, Xue,et al. Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2011,59(12):1562-1566.
APA Hu, Zhuo.,Zhan, Rui.,Du, Xue.,Su, Jia.,Li, Xiao-Nian.,...&Pu, Jian-Xin.(2011).Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi.CHEMICAL & PHARMACEUTICAL BULLETIN,59(12),1562-1566.
MLA Hu, Zhuo,et al."Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi".CHEMICAL & PHARMACEUTICAL BULLETIN 59.12(2011):1562-1566.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
201203190024.pdf(750KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Hu, Zhuo]的文章
[Zhan, Rui]的文章
[Du, Xue]的文章
百度学术
百度学术中相似的文章
[Hu, Zhuo]的文章
[Zhan, Rui]的文章
[Du, Xue]的文章
必应学术
必应学术中相似的文章
[Hu, Zhuo]的文章
[Zhan, Rui]的文章
[Du, Xue]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。