Trichiliasinenoids A-C, three 6,7-secomexicanolide limonoids with a 7,29-linkage from Trichilia sinensis
Cao, Dong-Hua1,3; Liao, Shang-Gao2; Yang, Lin1; Li, Xiao-Nian4; Wu, Bin5; Zhang, Ping1; Guo, Juan1; Xiao, Chun-Fen1; Hu, Hua-Bin1; Xu, You-Kai1
2017-08-16
发表期刊TETRAHEDRON LETTERS
ISSN0040-4039
卷号58期号:33页码:3283-3286
摘要Trichiliasinenoids A C (1-3), three new limonoids with an unprecedented C-29-C-7 connecting carbon skeleton formed by migration of C-7 from C-6 to C-29 of a mexicanolide-type limonoid precursor were isolated from the leaves and twigs of Trichilia sinensis. Their structures were assigned by spectroscopic analysis, and the absolute configurations were determined by X-ray crystallography (1) and ECD calculation (2 and 3). A possible biosynthetic pathway of 1 was also proposed. Compound 2 exhibited moderate cytotoxicity against HL-60 cells and weak cytotoxicity against SMMC-7721cells. (C) 2017 Elsevier Ltd. All rights reserved.
关键词Trichilia Sinensis Mexicanolide-type Limonoids Structure Elucidation Cytotoxicity
学科领域Chemistry, Organic
DOI10.1016/j.tetlet.2017.07.029
收录类别SCI
语种英语
WOS记录号WOS:000407524200019
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/54918
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Key Lab Trop Plant Resources & Sustainable Use Xi, Mengla 666303, Yunnan, Peoples R China
2.Guizhou Med Univ, Sch Pharm, Engn Res Ctr Dev & Applicat Ethn Medicines & TCM, 9 Beijing Rd, Guiyang 550004, Guizhou, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
5.South Cent Univ Nat, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China
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GB/T 7714
Cao, Dong-Hua,Liao, Shang-Gao,Yang, Lin,et al. Trichiliasinenoids A-C, three 6,7-secomexicanolide limonoids with a 7,29-linkage from Trichilia sinensis[J]. TETRAHEDRON LETTERS,2017,58(33):3283-3286.
APA Cao, Dong-Hua.,Liao, Shang-Gao.,Yang, Lin.,Li, Xiao-Nian.,Wu, Bin.,...&Xu, You-Kai.(2017).Trichiliasinenoids A-C, three 6,7-secomexicanolide limonoids with a 7,29-linkage from Trichilia sinensis.TETRAHEDRON LETTERS,58(33),3283-3286.
MLA Cao, Dong-Hua,et al."Trichiliasinenoids A-C, three 6,7-secomexicanolide limonoids with a 7,29-linkage from Trichilia sinensis".TETRAHEDRON LETTERS 58.33(2017):3283-3286.
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