中国科学院昆明植物研究所机构知识库
Advanced  
KIB OpenIR  > 植物化学与西部植物资源持续利用国家重点实验室  > 期刊论文
题名: Sesquiterpene and Norsesquiterpene Derivatives from Sanicula lamelligera and Their Biological Evaluation
作者: Li, Xue-Song1, 2; Zhou, Xiao-Jiang2; Zhang, Xing-Jie3; Su, Jia1; Li, Xue-Jing2; Yan, Yong-Ming1, 4; Zheng, Yong-Tang3; null(李艳)1; Yang, Liu-Meng3; null(程永现)1
刊名: JOURNAL OF NATURAL PRODUCTS
关键词: EUROPAEA L ; LITSEA-VERTICILLATA ; PLANUM L ; CONSTITUENTS ; SAPONINS ; TERPENOIDS ; LEAVES
英文摘要: Fourteen sesquiterpene and norsesquiterpene derivatives, comprising six different carbon skeletons, were isolated from Sanicula lamelligera. Saniculamoid A1 (1a) is an oxidation product of saniculamoid A (1), created by the transition of a formyl group to a carboxylic acid group after a period of storage in air. The known compounds 5-14 were identified in Sanicula plants for the first time. The compounds were evaluated for their anti-HIV-1, cytostatic, and nitric-oxide-production-inhibiting activities using in vitro cellular assays. The results showed that 1,5-naphthalenediol inhibited nitric oxide production in lipopolysaccharide-stimulated RAW 264.7 cells with an IC50 value of 28.1 mu M and was active toward five cancer cell lines with IC50 values in the 31.1-41.6 mu M range.
出版日期: 2011-06-01
卷号: 74, 期号:6, 页码:1521-1525
DOI标识: 10.1021/np200146x
语种: 英语
ISSN号: 0163-3864
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/5479
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
201203190053.pdf(932KB)----开放获取--View 联系获取全文

作者单位: 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Hunan Univ Chinese Med, Coll Pharm, Changsha 410208, Hunan, Peoples R China
3.Chinese Acad Sci, Kunming Inst Zool, Lab Mol Immunopharmacol, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Peoples R China
4.Chengdu Univ Tradit Chinese Med, Coll Pharm, Chengdu 610075, Peoples R China

Recommended Citation:
Li, XS; Zhou, XJ; Zhang, XJ; Su, J; Li, XJ; Yan, YM; Zheng, YT; Li, Y; Yang, LM; Cheng, YX.Sesquiterpene and Norsesquiterpene Derivatives from Sanicula lamelligera and Their Biological Evaluation,JOURNAL OF NATURAL PRODUCTS,2011,74(6):1521-1525
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Li, Xue-Song]'s Articles
[Zhou, Xiao-Jiang]'s Articles
[Zhang, Xing-Jie]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Li, Xue-Song]‘s Articles
[Zhou, Xiao-Jiang]‘s Articles
[Zhang, Xing-Jie]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: 201203190053.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院昆明植物研究所 - Feedback
Powered by CSpace