Amaryllidaceae Alkaloids from Lycoris radiata
Feng, Tao; Wang, Yuan-Yuan; Su, Jia; Li, Yan; Cai, Xiang-Hai; Luo, Xiao-Dong
Corresponding AuthorLuo, XD (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, 132 Lanhei Rd, Kunming 650204, Peoples R China
AbstractA phytochemical investigation on bulbs of Lycoris radiata resulted in the isolation of three new Amaryllidaceae alkaloids, named 5,6-dehydrodihydrolycorine (1), 6 beta-acetoxycrinamine (2), and (+)-8-O-acetylhomolycorine alpha-N-oxide (3), together with eleven known alkaloids, 4-14. The structures of the new alkaloids were established by means of spectroscopic methods, and the known compounds were identified by comparison of their data with those in the literature. Compound 2 showed cytotoxicity against HL-60, A-549, and MCF-7 cells, with IC(50) values of 8.1, 24.3, and 15.0 mu m, respectively.
KeywordNarcissus Alkaloids Racemic Lycoramine Ascorbic-acid Galanthamine (&-)-lycoramine Biosynthesis Constituents
Subject AreaChemistry
Indexed BySCI ; IC
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000287374800023
Citation statistics
Cited Times:17[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
AffiliationChinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
Recommended Citation
GB/T 7714
Feng, Tao,Wang, Yuan-Yuan,Su, Jia,et al. Amaryllidaceae Alkaloids from Lycoris radiata[J]. HELVETICA CHIMICA ACTA,2011,94(1):178-183.
APA Feng, Tao,Wang, Yuan-Yuan,Su, Jia,Li, Yan,Cai, Xiang-Hai,&Luo, Xiao-Dong.(2011).Amaryllidaceae Alkaloids from Lycoris radiata.HELVETICA CHIMICA ACTA,94(1),178-183.
MLA Feng, Tao,et al."Amaryllidaceae Alkaloids from Lycoris radiata".HELVETICA CHIMICA ACTA 94.1(2011):178-183.
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