Amaryllidaceae Alkaloids from Lycoris radiata
Feng, Tao; Wang, Yuan-Yuan; Su, Jia; Li, Yan; Cai, Xiang-Hai; Luo, Xiao-Dong
通讯作者Luo, XD (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, 132 Lanhei Rd, Kunming 650204, Peoples R China
2011
发表期刊HELVETICA CHIMICA ACTA
ISSN0018-019X
卷号94期号:1页码:178-183
摘要A phytochemical investigation on bulbs of Lycoris radiata resulted in the isolation of three new Amaryllidaceae alkaloids, named 5,6-dehydrodihydrolycorine (1), 6 beta-acetoxycrinamine (2), and (+)-8-O-acetylhomolycorine alpha-N-oxide (3), together with eleven known alkaloids, 4-14. The structures of the new alkaloids were established by means of spectroscopic methods, and the known compounds were identified by comparison of their data with those in the literature. Compound 2 showed cytotoxicity against HL-60, A-549, and MCF-7 cells, with IC(50) values of 8.1, 24.3, and 15.0 mu m, respectively.
关键词Narcissus Alkaloids Racemic Lycoramine Ascorbic-acid Galanthamine (&-)-lycoramine Biosynthesis Constituents
学科领域Chemistry
收录类别SCI ; IC
语种英语
WOS记录号WOS:000287374800023
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5419
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
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GB/T 7714
Feng, Tao,Wang, Yuan-Yuan,Su, Jia,et al. Amaryllidaceae Alkaloids from Lycoris radiata[J]. HELVETICA CHIMICA ACTA,2011,94(1):178-183.
APA Feng, Tao,Wang, Yuan-Yuan,Su, Jia,Li, Yan,Cai, Xiang-Hai,&Luo, Xiao-Dong.(2011).Amaryllidaceae Alkaloids from Lycoris radiata.HELVETICA CHIMICA ACTA,94(1),178-183.
MLA Feng, Tao,et al."Amaryllidaceae Alkaloids from Lycoris radiata".HELVETICA CHIMICA ACTA 94.1(2011):178-183.
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