Two New Lignans and Anti-HBV Constituents from Illicium henryi
Liu, Ji-Feng1,2; Jiang, Zhi-Yong1; Geng, Chang-An1,2; Zhang, Quan1,2; Shi, Yao3; Ma, Yun-Bao1; Zhang, Xue-Mei1; Chen, Ji-Jun1
2011-04-01
发表期刊CHEMISTRY & BIODIVERSITY
ISSN1612-1872
卷号8期号:4页码:692-698
摘要Two new lignans, dihydrodehydrodiconiferyl alcohol 9-O-beta-D-(3 ''-O-acetyl)-xylopyranoside (1) and threo-4,9,9'-trihydroxy-3,3'-dimethoxy-8-O-4'-neolignan 7-O-alpha-rhamnopyranoside (2) were isolated from Illicium henryi, together with ten known compounds, 3-12. Their structures were elucidated by extensive spectroscopic analyses. The anti-hepatitis B virus (anti-HBV) activity of compounds 1-12 inhibiting HBV surface antigen (HBsAg) and HBV e antigen (HBeAg) secretion on Hep G2.2.15 cell line was evaluated. (-)-Dihydrodehydrodiconiferyl alcohol (4) showed moderate inhibitory activity on both HBsAg and HBeAg secretion with IC(50) values of 0.06 and 0.53 mm, respectively.
关键词Prenylated C-6-c-3 Compounds Glycosides Bark Sesquiterpene Neolignan Difengpi Leaves
资助信息National Science Foundation of China for Distinguished Young Scholars[81025023]; Chinese Academy of Sciences[GJHZ200818]; CAS-Croucher Foundation[CAS-CF07/08.SC03]
学科领域Biochemistry & Molecular Biology ; Chemistry
收录类别SCI
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Chemistry
WOS类目Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS记录号WOS:000289859700014
引用统计
被引频次:16[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5409
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Hawley & Hazel Chem ZS Co Ltd, Zhongshan 528411, Peoples R China
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Liu, Ji-Feng,Jiang, Zhi-Yong,Geng, Chang-An,et al. Two New Lignans and Anti-HBV Constituents from Illicium henryi[J]. CHEMISTRY & BIODIVERSITY,2011,8(4):692-698.
APA Liu, Ji-Feng.,Jiang, Zhi-Yong.,Geng, Chang-An.,Zhang, Quan.,Shi, Yao.,...&Chen, Ji-Jun.(2011).Two New Lignans and Anti-HBV Constituents from Illicium henryi.CHEMISTRY & BIODIVERSITY,8(4),692-698.
MLA Liu, Ji-Feng,et al."Two New Lignans and Anti-HBV Constituents from Illicium henryi".CHEMISTRY & BIODIVERSITY 8.4(2011):692-698.
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