中国科学院昆明植物研究所机构知识库
Advanced  
KIB OpenIR  > 植物化学与西部植物资源持续利用国家重点实验室  > 期刊论文
题名: The role of MC1R gene in buffalo coat color
作者: Miao YongWang1, 2; Wu GuiSheng3; Wang Lei2; Li DaLin4; Tang ShouKun5; Liang JianPing2; Mao HuaMing2; null(罗怀容)3; Zhang YaPing1, 6
刊名: SCIENCE CHINA-LIFE SCIENCES
关键词: Buffalo ; coat color ; MC1R
英文摘要: Melanocortin-1 receptor (MC1R) plays a major role in pigmentation in many species. To investigate if the MC1R gene is associated with coat color in water buffalo, the coding region of MC1R gene of 216 buffalo samples was sequenced, which included 49 black river buffalo (Murrah and Nili-Ravi), 136 swamp buffalo (Dehong, Diandongnan, Dechang, Guizhou, and Xilin) with white and gray body, and 31 hybrid offspring of river buffalo Nili-Ravi (or Murrah) and swamp buffalo. Among the three variation sites found, SNP684 was synonymous, while SNP310 and SNP384 were nonsynonymous, leading to p.S104G and p.I128M changes, respectively. Only Individuals carrying homozygote E-BR/E-BR were black. The genotype and phenotype analysis of the hybrid offspring of black river buffalo and gray swamp buffalo further revealed that the river buffalo type allele E-BR or the allele carrying the amino acid p.104S was important for the full function of MC1R. The in silico functional analysis showed that the amino acid substitutions p.G104S and p.M128I had significant impact on the function of MC1R. Above results indicate that the allele E-BR or the allele carrying the amino acid p.104S was associated with the black coat color in buffalo.
出版日期: 2010-02-01
卷号: 53, 期号:2, 页码:267-272
DOI标识: 10.1007/s11427-010-0026-3
语种: 英语
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/5178
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
201203210002.pdf(1385KB)----开放获取--View Download

作者单位: 1.Yunnan Univ, Lab Conservat & Utilizat Bioresource, Kunming 650091, Peoples R China
2.Yunnan Agr Univ, Fac Anim Sci & Technol, Kunming 650201, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China
4.Yunnan Inst Buffalo Sci & Technol, Kunming 650021, Peoples R China
5.Anim Husb & Vet Stn Luxi City, Luxi 678400, Peoples R China
6.Chinese Acad Sci, State Key Lab Genet Resources & Evolut, Kunming Inst Zool, Kunming 650223, Peoples R China

Recommended Citation:
Miao, YW; Wu, GS; Wang, L; Li, DL; Tang, SK; Liang, JP; Mao, HM; Luo, HR; Zhang, YP.The role of MC1R gene in buffalo coat color,SCIENCE CHINA-LIFE SCIENCES,2010,53(2):267-272
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Miao YongWang]'s Articles
[Wu GuiSheng]'s Articles
[Wang Lei]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Miao YongWang]‘s Articles
[Wu GuiSheng]‘s Articles
[Wang Lei]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: 201203210002.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2018  中国科学院昆明植物研究所 - Feedback
Powered by CSpace