| Spirostanol saponins from Ypsilandra parviflora induce platelet aggregation | |
Lu, Ting-Xiang1,3; Shu, Tong1,2; Qin, Xu-Jie1 ; Ni, Wei1; Ji, Yun-Heng4; Chen, Qi-Run1,5; Khan, Afsar6; Zhao, Qing5; Liu, Hai-Yang1
| |
| 2017-07-01 | |
| 发表期刊 | STEROIDS
 |
| 卷号 | 123页码:55-60 |
| 摘要 | Phytochemical investigation on the whole plants of Ypsilandra parviflora led to the isolation of seven new spirostanol saponins, named ypsiparosides A-G, together with 14 known saponins. Their structures were unambiguously established based on extensive spectroscopic evidence and chemical methods. The induced rabbit platelet aggregation activities of the isolates were tested. Compounds 4, 15, and 17 showed maximal platelet aggregation rates ranging from 43 to 55% at a concentration of 300 mu g/mL. Further experiments exhibited that compounds 4, 15, and 17 possessed EC50 values of 642.9, 95.3, and 300.8 mu g/mL, respectively. |
| 关键词 | Ypsilandra Parviflora Liliaceae Spirostanol Saponins Ypsiparosides A-g Induced Platelet Aggregation Activity |
| DOI | 10.1016/j.steroids.2017.05.004 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000403131400008 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/51359 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Qiannan Med Coll Nationalities, Duyun 558000, Peoples R China 4.Chinese Acad Sci, Kunming Inst Bot, Key Lab Plant Biodivers & Biogeog East Asia, Kunming 650201, Peoples R China 5.Yunnan Univ TCM, Coll Tradit Chinese Med, Kunming 650500, Peoples R China 6.COMSATS Inst Informat Technol, Dept Chem, Abbottabad 22060, Pakistan |
| 推荐引用方式 GB/T 7714 | Lu, Ting-Xiang,Shu, Tong,Qin, Xu-Jie,et al. Spirostanol saponins from Ypsilandra parviflora induce platelet aggregation[J]. STEROIDS,2017,123:55-60. |
| APA | Lu, Ting-Xiang.,Shu, Tong.,Qin, Xu-Jie.,Ni, Wei.,Ji, Yun-Heng.,...&Liu, Hai-Yang.(2017).Spirostanol saponins from Ypsilandra parviflora induce platelet aggregation.STEROIDS,123,55-60. |
| MLA | Lu, Ting-Xiang,et al."Spirostanol saponins from Ypsilandra parviflora induce platelet aggregation".STEROIDS 123(2017):55-60. |
| 条目包含的文件 | 下载所有文件 | |||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| lu2017.pdf（254KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论