Dibenzocyclooctadiene lignans from the fruits of Schisandra wilsoniana and their anti-HIV-1 activities
Yang, Guang-Yu1,2; Li, Yin-Ke2,3; Wang, Rui-Rui4,5; Xiao, Wei-Lie1; Yang, Liu-Meng4,5; Pu, Jian-Xin1; Zheng, Yong-Tang4,5; Sun, Han-Dong1
2010
发表期刊JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
ISSN1028-6020
卷号12期号:6页码:470-476
摘要Three new dibenzocyclooctadiene lignans, wilsonilignans A-C (1-3), together with nine known ones, were isolated from the fruits of Schisandra wilsoniana. The structures of 1-3 were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1-3 were also evaluated for their anti-HIV-1 activities and showed bioactivity with EC50 values of 3.26, 6.18, and 2.87g/ml, respectively.
关键词Schisandra Wilsoniana Fruits Dibenzocyclooctadiene Lignans Anti-hiv-1 Activity
资助信息NSFC [30830115, 20802082]; Chinese Academy of Sciences [KSCX1-YW-R-24]; 973 programs [2009CB522300, 2009CB940900]; Young Academic and Technical Leader Rising Foundation of Yunnan Province [2006PY01-47]
学科领域Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1080/10286020.2010.489823
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000278787000009
引用统计
被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4938
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Yunnan Acad Tobacco Sci, Key Lab Tobacco Chem Yunnan Prov, Kunming 650106, Peoples R China
3.Yunnan Natl Univ, Sch Chem & Biotechnol, Kunming 650031, Peoples R China
4.Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Peoples R China
5.Chinese Acad Sci, Kunming Inst Zool, Lab Mol Immunopharmacol, Kunming 650223, Peoples R China
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Yang, Guang-Yu,Li, Yin-Ke,Wang, Rui-Rui,et al. Dibenzocyclooctadiene lignans from the fruits of Schisandra wilsoniana and their anti-HIV-1 activities[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2010,12(6):470-476.
APA Yang, Guang-Yu.,Li, Yin-Ke.,Wang, Rui-Rui.,Xiao, Wei-Lie.,Yang, Liu-Meng.,...&Sun, Han-Dong.(2010).Dibenzocyclooctadiene lignans from the fruits of Schisandra wilsoniana and their anti-HIV-1 activities.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,12(6),470-476.
MLA Yang, Guang-Yu,et al."Dibenzocyclooctadiene lignans from the fruits of Schisandra wilsoniana and their anti-HIV-1 activities".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 12.6(2010):470-476.
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