Cytotoxic ent-Kaurane Diterpenoids from Isodon rubescens var. lushiensis
Luo, Xiao1; Pu, Jian-Xin1; Xiao, Wei-Lie1; Zhao, Yong1; Gao, Xue-Mei1; Li, Xiao-Nian1; Zhang, Hai-Bo1,2; Wang, Yuan-Yuan1; Li, Yan1; Sun, Han-Dong1
2010-06-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号73期号:6页码:1112-1116
摘要Ten new ent-kaurane diterpenoids, isolushinins A-J (1-10), together with 20 known compounds, were isolated from the aerial parts of Isodon rubescens var. lushiensis. The structures of 1-10 were elucidated by spectroscopic analysis. Several of the compounds isolated were evaluated for their cytotoxicity against the HL-60, SMMC-7721, A-549, SK-BR-3, and PANC-1 human cancer cell lines, and some exhibited quite potent inhibitory activities.
关键词Cycloartane Triterpene Saponins Sequence Variation Black Cohosh Foetida l Glycosides Racemosa Actaea Proliferation Ranunculaceae Phylogeny
资助信息NSFC [30772637, 30830119]; NSFC-Joint Foundation of Yunnan Province [U0832602]; Major State Basic Research Development Program of China [2009CB522300, 2009CB940900]; Natural Science Foundation of Yunnan Province [2008CD162]; CAS [KSCX2-YW-R-25]
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np100110u
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000279070300016
引用统计
被引频次:14[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4896
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
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Luo, Xiao,Pu, Jian-Xin,Xiao, Wei-Lie,et al. Cytotoxic ent-Kaurane Diterpenoids from Isodon rubescens var. lushiensis[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(6):1112-1116.
APA Luo, Xiao.,Pu, Jian-Xin.,Xiao, Wei-Lie.,Zhao, Yong.,Gao, Xue-Mei.,...&Sun, Han-Dong.(2010).Cytotoxic ent-Kaurane Diterpenoids from Isodon rubescens var. lushiensis.JOURNAL OF NATURAL PRODUCTS,73(6),1112-1116.
MLA Luo, Xiao,et al."Cytotoxic ent-Kaurane Diterpenoids from Isodon rubescens var. lushiensis".JOURNAL OF NATURAL PRODUCTS 73.6(2010):1112-1116.
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